Search Result "lead optimi-zation"


New Lead Structures in Antifungal Drug Discovery

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 5 Year: 2011 Page: 733-766
Author(s): Chunquan Sheng, Wannian Zhang

Lead Optimization of Melanin Concentrating Hormone Receptor 1 Antagonists with low hERG Channel Activity

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1152-1157
Author(s): Andrew S. Judd, Andrew J. Souers, Philip R. Kym

Research Article

Modifications of Isoalantolactone Leading to Effective Anti-bacterial and Anti-viral Compounds

Journal: Letters in Drug Design & Discovery
Volume: 18 Issue: 7 Year: 2021 Page: 686-700
Author(s): Sergey S. Patrushev,Lyubov G. Burova,Anna A. Shtro,Tatyana V. Rybalova,Dmitry S. Baev,Il’ya V. Shirokikh,Alexander N. Evstropov,Elvira E. Shults

Anti Cancer Activity on Graviola, an Exciting Medicinal Plant Extract vs Various Cancer Cell Lines and a Detailed Computational Study on its Potent Anti-Cancerous Leads

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 1666-1673
Author(s): Jeno Paul, R. Gnanam, R. M. Jayadeepa, L. Arul

Review Article

The Structure–property Relationships of Clinically Approved ProteinKinase Inhibitors

Journal: Current Medicinal Chemistry
Volume: 30 Issue: 22 Year: 2023 Page: 2518-2541
Author(s):

Structure-Based Drug Design Strategies in Medicinal Chemistry

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 9 Year: 2009 Page: 771-790
Author(s):

Review Article

Combating Diseases with Computational Strategies Used for Drug Design and Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 32 Year: 2018 Page: 2743-2773
Author(s): Farahnaz R. Makhouri,Jahan B. Ghasemi

An Approach to Rational Ligand-Design Based on a Thermodynamic Analysis

Journal: Recent Patents on Biotechnology
Volume: 4 Issue: 3 Year: 2010 Page: 183-188
Author(s): Mihoko Ui, Kouhei Tsumoto

Methods for Integrating and Handling Complex Optimization Problems in the Process Industries

Journal: Recent Patents on Chemical Engineering
Volume: 2 Issue: 2 Year: 2009 Page: 123-127
Author(s): Edwin Zondervan, Andre B. de Haan

Nitric Oxide as a Marker for Levo-Thyroxine Therapy in Subclinical Hypothyroid Patients

Journal: Current Vascular Pharmacology
Volume: 14 Issue: 3 Year: 2016 Page: 266-270
Author(s): Milan Obradovic,Zoran Gluvic,Emina Sudar-Milovanovic,Anastasija Panic,Jovana Trebaljevac,Vladan Bajic,Milos Zarkovic,Esma R Isenovic

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