Search Result "kinase-domains"

The Src Homology-2 Domains (SH2 Domains) of the Protein Tyrosine Kinase p56 lck Structure, Mechanism and Drug Design

Journal: Current Drug Targets
Volume: 1 Issue: 4 Year: 2000 Page: 365-386
Author(s): R. J. Broadbridge, R. P. Sharma

Research Article

Chemical IN04 Inhibits the Kinase Domain not the ROC Domain of LRRK1: Results from Homology Modeling and Molecular Docking

Journal: Medicinal Chemistry
Volume: 17 Issue: 10 Year: 2021 Page: 1140-1150
Author(s): Zhenhang Chen,Weirong Xing,Li Fan

Synthetic Src-Kinase Domain Inhibitors and Their Structural Requirements

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 7 Issue: 6 Year: 2007 Page: 660-680
Author(s): Silvia Schenone, Fabrizio Manetti, Maurizio Botta

Expression, Purification, and Characterization of an Enzymatically Active Truncated Human Rho-Kinase I (ROCK I) Domain Expressed in Sf-9 Insect Cells

Journal: Protein & Peptide Letters
Volume: 13 Issue: 4 Year: 2006 Page: 369-376
Author(s): Sanjay S. Khandekar, Tracey Yi, Ed Dul, Lois L. Wrigh, Susan Chen, Gilbert F. Scott, Gary K. Smith, Dennis Lee, Erding Hu, Robert B. Kirkpatrick

Insight into the Mechanism of Domain Movements and their Role in Enzyme Function: Example of 3-Phosphoglycerate Kinase

Journal: Current Protein & Peptide Science
Volume: 11 Issue: 2 Year: 2010 Page: 118-147
Author(s): M. Vas, A. Varga, E. Graczer

Statistics of Catalytic Domain Sequences in Protein Kinases Vs Non-Kinases

Journal: Protein & Peptide Letters
Volume: 14 Issue: 6 Year: 2007 Page: 518-527
Author(s): Rajani R. Joshi, Chaithanya Manda

Indolactam and Benzolactam Compounds as New Medicinal Leads with Binding Selectivity for C1 Domains of Protein Kinase C Isozymes

Journal: Current Pharmaceutical Design
Volume: 10 Issue: 1 Year: 2004 Page: 1371-1385
Author(s): Kazuhiro Irie, Yu Nakagawa, Hajime Ohigashi

Recent Findings Confirm LIM Domain Kinases as Emerging Target Candidates for Cancer Therapy

Journal: Current Cancer Drug Targets
Volume: 12 Issue: 5 Year: 2012 Page: 543-560
Author(s): F. Manetti

A Case Study from the Chemistry Core of the Pittsburgh Molecular Library Screening Center: The Polo-like Kinase Polo-Box Domain (Plk1- PBD)

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1194-1205
Author(s): Peter Wipf, David Arnold, Karen Carter, Shuzhi Dong, Paul A. Johnston, Elizabeth Sharlow, John S. Lazo, Donna H. Huryn

Mitoxantrone Targets the ATP-binding Site of FAK, Binds the FAK Kinase Domain and Decreases FAK, Pyk-2, c-Src, and IGF-1R In Vitro Kinase Activities

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 4 Year: 2013 Page: 546-554
Author(s): Vita M. Golubovskaya, Baotran Ho, Min Zheng, Andrew Magis, David Ostrov, William G. Cance

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