Search Result "isosterism"


Isosteric and Spatial Considerations of Drugs

Ebook: Medicinal Chemistry for Pharmacy Students
Volume: 1 Year: 2018
Author(s): M. O. Faruk Khan,Timothy J. Hubin
Doi: 10.2174/9781681086873118010008

Synthesis and Enzyme Inhibitory Activities of Novel Peptide Isosteres

Journal: Current Medicinal Chemistry
Volume: 9 Issue: 2 Year: 2002 Page: 2243-2270
Author(s): Natarajan Venkatesan, Byeang Hyean Kim

Phosphate Isosteres in Medicinal Chemistry

Journal: Current Medicinal Chemistry
Volume: 12 Issue: 2 Year: 2005 Page: 3127-3141
Author(s): C. S. Rye, J. B. Baell

Minor-Groove Binding Agents: Rational Design of Carboxamide Bond Isosteres

Journal: Current Topics in Medicinal Chemistry
Volume: 15 Issue: 14 Year: 2015 Page: 1359-1371
Author(s): Chi Wi Ong,Ping Syun Yang

Benzoxazine and Benzodioxine as Indole Isosteres in Indolocarbazoles Series: Synthesis and Biological Evaluation

Journal: Letters in Organic Chemistry
Volume: 7 Issue: 2 Year: 2010 Page: 121-126
Author(s): Nathalie Ayerbe, Sylvain Routier, Isabelle Gillaizeau, Sebastien Tardy, Gerard Coudert

New Cathepsin D Inhibitorswith Hydroxyethylamine Isosteres: Preparation and Characterization

Journal: Medicinal Chemistry
Volume: 2 Issue: 1 Year: 2006 Page: 27-38
Author(s): S. E. Hatfield, W. E. Godwin, K. Sayyar, J. F. Lindley, A. W. Green, C. J. Trana, M. S. McConnell, R. M. McConnell

Targeting Enzymes with Phosphonate-Based Inhibitors: Mimics of Tetrahedral Transition States and Stable Isosteric Analogues of Phosphates

Journal: Current Enzyme Inhibition
Volume: 2 Issue: 1 Year: 2006 Page: 61-72
Author(s): L. Azema, R. Baron, S. Ladame

Inhibition of BACE-1 by Hydroxyethylsulfide, Hydroxyethylamine and Hydroxyethylurea Isosteric Replacements

Journal: Letters in Drug Design & Discovery
Volume: 2 Issue: 2 Year: 2005 Page: 109-112
Author(s): L. Rizzi, S. Romeo

Effects of Introducing Silicon Isosteres in COX-2 Inhibitors: A Preliminary In Silico Evaluation

Journal: Medicinal Chemistry
Volume: 1 Issue: 3 Year: 2005 Page: 215-226
Author(s): Patrick Englebienne

Biphenyl Amides and Isosteres as MCH R1 Antagonists

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1455-1470
Author(s): Donald L. Hertzog, David R. Witty

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