Search Result "intramembrane proteolysis"


Structural and Functional Determinants of γ-Secretase, an Intramembrane Protease Implicated in Alzheimers Disease

Journal: Current Genomics
Volume: 8 Issue: 8 Year: 2007 Page: 531-549
Author(s): Patrick C. Fraering

Ectodomain Shedding and Regulated Intracellular Proteolysis in the Central Nervous System

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 10 Issue: 4 Year: 2010 Page: 337-359
Author(s): Pavel Montes de Oca-B

An Overview of Notch Signaling in Adult Tissue Renewal and Maintenance

Journal: Current Alzheimer Research
Volume: 9 Issue: 2 Year: 2012 Page: 227-240
Author(s): Chihiro Sato, Guojun Zhao, Ma. Xenia G. Ilagan

Similar Mechanisms Regulated by γ-Secretase are Involved in Both Directions of the Bi-Directional Notch-Delta Signaling Pathway as well as Play a Potential Role in Signaling Events Involving Type 1 Transmembrane Proteins

Journal: Current Stem Cell Research & Therapy
Volume: 3 Issue: 4 Year: 2008 Page: 288-302
Author(s): Kohzo Nakayama, Hisashi Nagase, Masahiro Hiratochi, Chang-Sung Koh, Takeshi Ohkawara

Alpha-Secretase Cleavage of the Amyloid Precursor Protein: Proteolysis Regulated by Signaling Pathways and Protein Trafficking

Journal: Current Alzheimer Research
Volume: 9 Issue: 2 Year: 2012 Page: 165-177
Author(s): Stefan F. Lichtenthaler

γ-Secretase Modulators

Journal: Current Alzheimer Research
Volume: 4 Issue: 5 Year: 2007 Page: 571-573
Author(s): Michael S. Wolfe

The What, Where, and How of γ-Secretase Complex Assembly

Ebook: Advances in Alzheimer's Research
Volume: 1 Year: 2013
Author(s): Daniel R. Dries,Gang Yu
Doi: 10.2174/9781608054954113010010

AICD Nuclear Signaling and Its Possible Contribution to Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 9 Issue: 2 Year: 2012 Page: 200-216
Author(s): Uwe Konietzko

ADAM10 as a Therapeutic Target for Cancer and Inflammation

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 2 Year: 2009 Page: 2288-2299
Author(s): Howard C. Crawford, Peter J. Dempsey, Gordon Brown, Liana Adam, Marcia L. Moss

Review Article

Role of γ-Secretase Inhibitors for the Treatment of Diverse Disease Conditions through Inhibition of Notch Signaling Pathway

Journal: Current Drug Targets
Volume: 22 Issue: 15 Year: 2021 Page: 1799-1807
Author(s): Arijit Mondal,Sankhadip Bose,Sabyasachi Banerjee,Dilipkumar Pal

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