Search Result "ibufenac"


Research Article

New Perspectives on Acyl Glucuronide Risk Assessment in Drug Discovery: Investigation of In vitro Stability, In situ Reactivity, and Bioactivation

Journal: Drug Metabolism Letters
Volume: 12 Issue: 2 Year: 2018 Page: 84-92
Author(s): Mithat Gunduz,Upendra A. Argikar,Amanda L. Cirello,Jennifer L. Dumouchel

Drug-S-Acyl-Glutathione Thioesters: Synthesis, Bioanalytical Properties, Chemical Reactivity, Biological Formation and Degradation

Journal: Current Drug Metabolism
Volume: 12 Issue: 3 Year: 2011 Page: 229-244
Author(s): Mark P. Grillo

Chemistry and Reactivity of Acyl Glucuronides

Journal: Current Drug Metabolism
Volume: 12 Issue: 3 Year: 2011 Page: 215-221
Author(s): Andrew V. Stachulski

A Developmental Approach to Drug-induced Liver Injury in Newborns and Children

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 27 Year: 2012 Page: 4581-4594
Author(s): G. Faa,J. Ekstrom,M. Castagnola,Y. Gibo,G. Ottonello,V. Fanos

Xenobiotic Acyl Glucuronides and Acyl CoA Thioesters as Protein- Reactive Metabolites With the Potential to Cause Idiosyncratic Drug Reactions

Journal: Current Drug Metabolism
Volume: 3 Issue: 4 Year: 2002 Page: 439-450
Author(s): Urs A. Boelsterli

Many Drugs and Phytochemicals Can Be Activated to Biological Reactive Intermediates

Journal: Current Drug Metabolism
Volume: 9 Issue: 4 Year: 2008 Page: 344-351
Author(s): William W. Johnson

In Vitro Evaluation of Potential Hepatotoxicity Induced by Drugs

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 1 Year: 2010 Page: 1963-1977
Author(s): M.J. Gomez-Lechon, A. Lahoz, L. Gombau, J.V. Castell, M.T. Donato

Drug Acyl Glucuronides: Reactivity and Analytical Implication

Journal: Current Pharmaceutical Analysis
Volume: 2 Issue: 3 Year: 2006 Page: 259-277
Author(s): Xiao-Xia Yang, Ze-Ping Hu, Urs Alex Boelsterli, Shu-Feng Zhou

Precision-Cut Organ Slices as a Tool to Study Toxicity and Metabolism of Xenobiotics with Special Reference to Non-Hepatic Tissues

Journal: Current Drug Metabolism
Volume: 3 Issue: 1 Year: 2002 Page: 39-59
Author(s): R. de Kanter, M. Monshouwer, D. K.F. Meijer, G. M.M. Groothuis

Pharmacogenomics in Drug Induced Liver Injury

Journal: Current Drug Metabolism
Volume: 10 Issue: 9 Year: 2009 Page: 956-970
Author(s): Raul J. Andrade, Jose A.G. Agundez, M. Isabel Lucena, Carmen Martinez, Raquel Cueto, Elena Garcia-Martin

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