Search Result "hit triage"
Hit Triage Using Efficiency Indices after Screening of Compound Libraries in Drug Discovery
Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1718-1724
Author(s): Allen B. Reitz, Garry R. Smith, Brett A. Tounge, Charles H. Reynolds
The Identification, Characterization and Optimization of Small Molecule Probes of Cysteine Proteases: Experiences of the Penn Center for Molecular Discovery with Cathepsin B and Cathepsin L
Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1206-1216
Author(s): Donna M. Huryn, Amos B. Smith III
A Collaborative Hit-to-Lead Investigation Leveraging Medicinal Chemistry Expertise with High Throughput Library Design, Synthesis and Purification Capabilities
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 123-130
Author(s): X. Yang, D. Parker, L. Whitehead, N. S. Ryder, B. Weidmann, M. Stabile-Harris, D. Kizer, M. McKinnon, A. Smellie, D. Powers
Integration of NMR and High-Throughput Screening
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 5 Issue: 8 Year: 2002 Page: 613-621
Author(s): Philip J. Hajduk, David J. Burns
High Throughput Screening Assay to Identify Modulators of IL-17 Expression
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 20 Issue: 9 Year: 2017 Page: 804-819
Author(s): Mohamed Boudjelal,Ana Maria Ruiz-Avendano,Gonzalo Colmenarejo,Sergio A. Senar-Sancho,Ashley Barnes,Stephen A. Harrison
The In Silico Drug Discovery Toolbox: Applications in Lead Discovery and Optimization
Journal: Current Medicinal Chemistry
Volume: 26 Issue: 2 Year: 2019 Page: 3838-3873
Author(s): Agostino Bruno,Gabriele Costantino,Luca Sartori,Marco Radi
Exploring Novel Target Space: A Need to Partner High Throughput Docking and Ligand-Based Similarity Searches?
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 1 Year: 2009 Page: 984-999
Author(s): Kumaran Shanmugasundaram, Alan C. Rigby
Integration of Virtual and High Throughput Screening in Lead Discovery Settings
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 1 Year: 2011 Page: 889-897
Author(s): Timea Polgar, Gyorgy M. Keseru
Applications of Biophysical Tools to Target-Based Discovery of Novel Antibacterial Leads
Journal: Current Drug Targets
Volume: 13 Issue: 3 Year: 2012 Page: 388-408
Author(s): Sushmita Lahiri, Steven Kazmirski, Gunther Kern, Gautam Sanyal
Enhanced Selectivity Screening of GPCR Ligands Using a Label-Free Cell Based Assay Technology
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 8 Year: 2009 Page: 812-823
Author(s): Ryan P. McGuinness, John M. Proctor, Debra L. Gallant, Carlo J. van Staden, Jenny T. Ly, Flora L. Tang, Paul H. Lee