Search Result "gefit-inib"


Epidermal Growth Factor Receptor (EGFR) and its Cross-Talks with Topoisomerases: Challenges and Opportunities for Multi-Target Anticancer Drugs

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 21 Year: 2016 Page: 3226-3236
Author(s): Monika Chauhan,Gourav Sharma,Gaurav Joshi,Raj Kumar

Research Article

Polyphyllin II Restores Sensitization of the Resistance of PC-9/ZD Cells to Gefitinib by a Negative Regulation of the PI3K/Akt/mTOR Signaling Pathway

Journal: Current Cancer Drug Targets
Volume: 17 Issue: 4 Year: 2017 Page: 376-385
Author(s): Ruzhen Zheng,Hao Jiang,Jinhui Li,Xinge Liu,Hongwei Xu

Clinical Trial

Clinical Impact of Gastric Acid Suppressants Use on the Efficacy of Gefitinib in Patients with Advanced Adenocarcinoma of the Lung Harboring Common EGFR Mutations

Journal: Clinical Cancer Drugs
Volume: 7 Issue: 1 Year: 2020 Page: 57-61
Author(s): Wang Chun Kwok,James Chung Man Ho,David Chi Leung Lam,Macy Mei Sze Lui,Mary Sau Man Ip,Terence Chi Chun Tam

Making the Most of Pathological Specimens: Molecular Diagnosis in Formalin-Fixed, Paraffin Embedded Tissue

Journal: Current Drug Targets
Volume: 13 Issue: 12 Year: 2012 Page: 1475-1487
Author(s): Jennifer A. Fairley,Katelyn Gilmour,Kathy Walsh

Optimizing Anti-EGFR Strategies in Cancer Treatment

Journal: Current Cancer Therapy Reviews
Volume: 3 Issue: 4 Year: 2007 Page: 267-275
Author(s): Luca Toschi, Giovanna Finocchiaro, Isabella Garassino, Fabio De Vincenzo, Elisabetta Campagnoli, Giovanni Luca Ceresoli, Raffaele Cavina, Paolo Andrea Zucali, Armando Santoro, Federico Cappuzzo

Small Molecule Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors in Non Small Cell Lung Cancer Treatment

Journal: Current Cancer Therapy Reviews
Volume: 3 Issue: 4 Year: 2007 Page: 226-235
Author(s): Clorinda Schettino, Maria Anna Bareschino, Paolo Maione, Antonio Rossi, Fortunato Ciardiello, Cesare Gridelli

HGF-MET in Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer

Journal: Current Signal Transduction Therapy
Volume: 6 Issue: 2 Year: 2011 Page: 228-233
Author(s): Seiji Yano, Wei Wang, Qi Li, Tadaaki Yamada, Shinji Takeuchi, Kunio Matsumoto, Yasuhiko Nishioka, Saburo Sone

Review Article

Pharmacokinetics of Gefitinib: Roles of Drug Metabolizing Enzymes and Transporters

Journal: Current Drug Delivery
Volume: 14 Issue: 2 Year: 2017 Page: 282-288
Author(s): Can Zhao,Shu-Yan Han,Ping-Ping Li

The Intriguing Interplay Between Therapies Targeting the Epidermal Growth Factor Receptor, the Hypoxic Microenvironment and Hypoxia-inducible Factors

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 5 Year: 2013 Page: 907-917
Author(s): An Wouters,Carolien Boeckx,Jan B. Vermorken,Danielle Van den Weyngaert,Marc Peeters,Filip Lardon

Targeting the Akt-pathway to Improve Radiosensitivity in Glioblastoma

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 5 Year: 2013 Page: 951-957
Author(s): Ravi S. Narayan,Carlos Alexandre Fedrigo,Lukas J.A. Stalpers,Brigitta G. Baumert,Peter Sminia

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