Search Result "electrophilic P450 metabolites"
Cytochromes P450 in the Bioactivation of Chemicals
Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 1 Year: 2004 Page: 1767-1788
Author(s): Costas Ioannides, David F. V. Lewis
Cytochromes P450: Role in Carcinogenesis and Relevance to Cancers
Journal: Current Drug Metabolism
Volume: 23 Issue: 5 Year: 2022 Page: 355-373
Author(s): Boon Hooi Tan,Chin Eng Ong
Inhibitory Properties of Trapping Agents: Glutathione, Potassium Cyanide, and Methoxylamine, Against Major Human Cytochrome P450 Isoforms
Journal: Drug Metabolism Letters
Volume: 3 Issue: 2 Year: 2009 Page: 125-129
Author(s): Chenghong Zhang, Susan Wong, Erlie M. Delarosa, Jane R. Kenny, Jason S. Halladay, Cornelis E. Hop, Siamak Cyrus Khojasteh-Bakht
Role of Oxidative Stress and Reactive Metabolites in Cytotoxicity & Mitotoxicity of Clozapine, Diclofenac and Nifedipine in CHO-K1 Cells In Vitro
Journal: Endocrine, Metabolic & Immune Disorders - Drug Targets
Volume: 23 Issue: 14 Year: 2023 Page: 1725-1739
Author(s):
Mechanism Study of N-Dephenylation Mediated through a N-para-Hydroxy Metabolite
Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 2 Year: 2006 Page: 101-114
Author(s): Jianyao Wang, William DeMaio, Appavu Chandrasekaran, Li Shen, Alvin C. Bach II, JoAnn Scatina, Rasmy Talaat
The Role of Cytochrome P450 in Cytotoxic Bioactivation: Future Therapeutic Directions
Journal: Current Cancer Drug Targets
Volume: 4 Issue: 3 Year: 2004 Page: 257-265
Author(s): P. H. Rooney, C. Telfer, M. C. E. McFadyen, W. T. Melvin, G. I. Murray
Are Chemically Reactive Metabolites Responsible for Adverse Reactions to Drugs?
Journal: Current Drug Metabolism
Volume: 3 Issue: 4 Year: 2002 Page: 351-366
Author(s): D. P. Williams, N. R. Kitteringham, D. J. Naisbitt, M. Pirmohamed, D. A. Smith, B. K. Park
Cytochrome P450 Expression in the Liver of Food-Producing Animals
Journal: Current Drug Metabolism
Volume: 7 Issue: 4 Year: 2006 Page: 335-348
Author(s): Costas Ioannides
Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Chemical Mechanisms, Structure-Activity Relationships and Relationship to Clinical Drug-Drug Interactions and Idiosyncratic Adverse Drug Reactions
Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 407-447
Author(s): Amit S. Kalgutkar, R. Scott Obach, Tristan S. Maurer
Multiple Oxidants in Cytochrome P450 Catalyzed Reactions Implications for Drug Metabolism
Journal: Current Drug Metabolism
Volume: 2 Issue: 1 Year: 2001 Page: 1-16
Author(s): Alfin D.N. Vaz