Search Result "elacridar"
A Simplified Protocol Employing Elacridar in Rodents: A Screening Model in Drug Discovery to Assess P-gp Mediated Efflux at the Blood Brain Barrier
Journal: Drug Metabolism Letters
Volume: 6 Issue: 2 Year: 2012 Page: 134-144
Author(s): Rajareddy Kallem,Chetan P. Kulkarni,Dakshay Patel,Megha Thakur,Michael Sinz,Sheelendra P. Singh,S. Shahe Mahammad,Sandhya Mandlekar
Substrates, Inhibitors and Activators of P-glycoprotein: Candidates for Radiolabeling and Imaging Perspectives
Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1703-1714
Author(s): Nicola A. Colabufo, Francesco Berardi, Maria Grazia Perrone, Elena Capparelli, Mariangela Cantore, Carmela Inglese, Roberto Perrone
Role of ATP-Binding Cassette Transporter Proteins in CNS Tumors: Resistance- Based Perspectives and Clinical Updates
Journal: Current Pharmaceutical Design
Volume: 26 Issue: 37 Year: 2020 Page: 4747-4763
Author(s): M. Asif,M. Usman,Shahid Ayub,Sahar Farhat,Zilli Huma,Jawad Ahmed,Mohammad A. Kamal,Deema Hussein,Aneela Javed,Ishaq Khan
Modulation and Absorption of Xenobiotics: The Synergistic Role of CYP450 and P-gp Activities in Cancer and Neurodegenerative Disorders
Journal: Current Drug Metabolism
Volume: 12 Issue: 8 Year: 2011 Page: 702-712
Author(s): Carmela Inglese, Maria Grazia Perrone, Francesco Berardi, Roberto Perrone, Nicola Antonio Colabufo
Kinetic Models for Measuring P-glycoprotein Function at the Blood-Brain Barrier with Positron Emission Tomography
Journal: Current Pharmaceutical Design
Volume: 22 Issue: 38 Year: 2016 Page: 5786-5792
Author(s): Mark Lubberink
Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions
Journal: Drug Metabolism Letters
Volume: 12 Issue: 1 Year: 2018 Page: 3-13
Author(s): Susan Wong,Utkarsh Doshi,Peter Vuong,Ning Liu,Suzanne Tay,Hoa Le,Mika Kosaka,Jane R. Kenny,Albert P. Li,Zhengyin Yan
The Tetrahydroisoquinoline Scaffold in ABC Transporter Inhibitors that Act as Multidrug Resistance (MDR) Reversers
Journal: Current Topics in Medicinal Chemistry
Volume: 22 Issue: 31 Year: 2022 Page: 2535-2569
Author(s): Maria Novella Romanelli
Carbon-11 Labeled Tracers for In Vivo Imaging of P-Glycoprotein Function: Kinetics, Advantages and Disadvantages
Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1820-1833
Author(s): Gert Luurtsema, Joost Verbeek, Mark Lubberink, Adriaan A. Lammertsma, Rudi Dierckx, Philip Elsinga, Albert D. Windhorst, Aren van Waarde
Relevance of Breast Cancer Resistance Protein to Brain Distribution and Central Acting Drugs: A Pharmacokinetic Perspective
Journal: Current Drug Metabolism
Volume: 19 Issue: 1 Year: 2018 Page: 1021-1041
Author(s): Joana Goncalves,Joana Bicker,Gilberto Alves,Ana Fortuna,Amilcar Falcao
Imaging of P-glycoprotein Function and Expression to Elucidate Mechanisms of Pharmacoresistance in Epilepsy
Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1785-1791
Author(s): Wolfgang Loscher, Oliver Langer