Search Result "deorphanization"


Chimeric and Promiscuous G Proteins in Drug Discovery and the Deorphanization of GPCRs

Journal: Drug Design Reviews - Online (Discontinued)
Volume: 2 Issue: 1 Year: 2005 Page: 66-79
Author(s): David C. New, Yung H. Wong

The Role of Natural Products in the Ligand Deorphanization of TRP Channels

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 1 Year: 2008 Page: 2-17
Author(s): G. Appendino, A. Minassi, A. Pagani, A. Ech-Chahad

Chemogenomics Approaches for Receptor Deorphanization and Extensions of the Chemogenomics Concept to Phenotypic Space

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1964-1977
Author(s): Eelke van der Horst, Julio E. Peironcely, Gerard J. P. van Westen, Olaf O. van den Hoven, Warren R. J. D. Galloway, David R. Spring, Joerg K. Wegner, Herman W. T. van Vlijmen, Ad P. IJzerman, John P. Overington, Andreas Bender

Chemical and Biological Profiling of an Annotated Compound Library Directed to the Nuclear Receptor Family

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 8 Year: 2005 Page: 763-772
Author(s): Montserrat Cases, Ricard Garcia-Serna, Kristina Hettne, Marc Weeber, Johan V. Lei, Scott Boyer, Jordi Mestres

Review Article

Free Fatty Acids-Sensing G Protein-Coupled Receptors in Drug Targeting and Therapeutics

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 31 Year: 2013 Page: 3855-3871
Author(s): Tomo Yonezawa,Riho Kurata,Kaori Yoshida,Masanori A. Murayama,Xiaofeng Cui,Akihiko Hasegawa

Molecular Determinants of Selective Agonist and Antagonist Binding to the Histamine H4 Receptor

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 6 Year: 2011 Page: 661-679
Author(s): Enade P. Istyastono, Chris de Graaf, Iwan J.P. de Esch, Rob Leurs

Concomitant CXCR4 and CXCR7 Expression Predicts Poor Prognosis in Renal Cancer

Journal: Current Cancer Drug Targets
Volume: 10 Issue: 7 Year: 2010 Page: 772-781
Author(s): C. DAlterio, C. Consales, M. Polimeno, R. Franco, L. Cindolo, L. Portella, M. Cioffi, R. Calemma, L. Marra, L. Claudio, S. Perdona, S. Pignata, G. Facchini, G. Carteni, N. Longo, L. Pucci, A. Ottaiano, S. Costantini, G. Castello, S. Scala

Recent Advances in Gut Nutrient Chemosensing

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 1 Year: 2012 Page: 28-34
Author(s): C. A. Nguyen, Y. Akiba, J. D. Kaunitz

Review Article

Recent Advances in Development of GPR40 Modulators (FFA1/FFAR1): An Emerging Target for Type 2 Diabetes

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 17 Issue: 11 Year: 2017 Page: 947-958
Author(s): Nutan Sharma,Sunita Bhagat,Tejpal Singh Chundawat

Computational Strategies to Incorporate GPCR Complexity in Drug Design

Ebook: Frontiers in Computational Chemistry
Volume: 1 Year: 2015
Author(s): Maria Marti-Solano,Agnieszka A. Kaczor,Ramon Guixà-González,Jana Selent
Doi: 10.2174/9781608058648115010003

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