Search Result "crystallographic assay"


Research Article

Elaboration of Novel TTK1 Inhibitory Leads via QSAR-Guided Selection of Crystallographic Pharmacophores Followed By In Vitro Assay

Journal: Current Computer-Aided Drug Design
Volume: 17 Issue: 4 Year: 2021 Page: 511-522
Author(s): Mahmoud A. Al-Sha'er,Mutasem O. Taha

Kinetic and Crystallographic Studies on Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in Complex with Iodoacetate

Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 3 Year: 2009 Page: 210-214
Author(s): Rafael V.C. Guido, Tatiane L. Balliano, Adriano D. Andricopulo, Glaucius Oliva

Structural Insight Into the Crucial Role of Ligand Chirality in the Activation of PPARs by Crystallographic Methods

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 7 Year: 2011 Page: 819-839
Author(s): F. Loiodice, G. Pochetti

Cross-Neutralizing Human Monoclonal Anti-HIV-1 Antibody 2F5: Preparation and Crystallographic Analysis of the Free and Epitope-Complexed Forms of its F ab Fragment

Journal: Protein & Peptide Letters
Volume: 8 Issue: 5 Year: 2001 Page: 413-418
Author(s): Steve Bryson, Annie Cunningham, Jason Ho, Rosemary C. Hynes, David E. Isenman, Brian H. Barber, Renate Kunert, Hermann Katinger, Michel Klein, Emil F. Pai

Research Article

Identification, Characterization and Molecular Modelling Studies of Schistosoma mansoni Dihydrofolate Reductase Inhibitors: From Assay Development to Hit Identification

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 5 Year: 2018 Page: 406-417
Author(s): Andre Lacerda Braga Teles,Roseane R. Silva,Michelle Ko,Glaucio Monteiro Ferreira,Samuel da Rocha Pita,Gustavo Henrique Goulart Trossini,Paulo Carvalho,Marcelo Santos Castilho

Lipophilic Mediated Assays for β-Hematin Inhibitors

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 3 Year: 2010 Page: 285-292
Author(s): Melissa D. Carter, Vanessa V. Phelan, Rebecca D. Sandlin, Brian O. Bachmann, David W. Wright

NMR Applications for Identifying β-TrCP Protein-Ligand Interactions

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 283-297
Author(s): J. Pons, V. Tanchou, J.-P. Girault, G. Bertho, N. Evrard-Todeschi

A High Throughput Fluorescence Polarization Assay for Inhibitors of the GoLoco Motif/G-alpha Interaction

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 5 Year: 2008 Page: 396-409
Author(s): Adam J. Kimple, Adam Yasgar, Mark Hughes, Ajit Jadhav, Francis S. Willard, Robin E. Muller, Christopher P. Austin, James Inglese, Gordon C. Ibeanu, David P. Siderovski, Anton Simeonov

Crystallographic Study and Biological Evaluation of 1,4-dimethyl-N-alkylcarbazoles†

Journal: Current Topics in Medicinal Chemistry
Volume: 15 Issue: 11 Year: 2015 Page: 973-979
Author(s): Carmela Saturnino,Anna Caruso,Pasquale Longo,Anna Capasso,Attilio Pingitore,Maria Cristina Caroleo,Erika Cione,Mariarita Perri,Francesco Nicolo,Viviana Mollica Nardo,Luigi Monsu Scolaro,Maria Stefania Sinicropi,Maria Rosaria Plutino,Hussein El-Kashef

Preliminary X-Ray Crystallographic Studies Of The Mycobacterium Tuberculosis Hsp16.3 Molecular Chaperone

Journal: Protein & Peptide Letters
Volume: 8 Issue: 6 Year: 2001 Page: 499-502
Author(s): Y. Chen, J. An, Y. Ding, H. Dai, Q. Mao, L. Feng, B. Liu, Y. Chang, F. Chen, H. He, H. Tang, Z. Chang, Z. Rao

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