Search Result "cryopreserved hepatocytes"
Assessment of Cryopreserved Hepatocytes as an Alternative to Fresh Hepatocytes forComparative InterspeciesMetabolism Studieswith Suitable Acceptance Criteria
Journal: Drug Metabolism Letters
Volume: 1 Issue: 2 Year: 2007 Page: 109-120
Author(s): Ziqiang (Zack) Cheng, Christine E. Herron, Gary Bowers, Mark de Serres
Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions
Journal: Drug Metabolism Letters
Volume: 12 Issue: 1 Year: 2018 Page: 3-13
Author(s): Susan Wong,Utkarsh Doshi,Peter Vuong,Ning Liu,Suzanne Tay,Hoa Le,Mika Kosaka,Jane R. Kenny,Albert P. Li,Zhengyin Yan
Application of a Convective-Dispersion Model to Predict In Vivo Hepatic Clearance from In Vitro Measurements Utilizing Cryopreserved Human Hepatocytes
Journal: Current Drug Metabolism
Volume: 4 Issue: 5 Year: 2003 Page: 357-369
Author(s): Ryan Niro, James P. Byers, Ronald L. Fournier, Kenneth Bachmann
Human Hepatocytes as a Tool for Studying Toxicity and Drug Metabolism
Journal: Current Drug Metabolism
Volume: 4 Issue: 4 Year: 2003 Page: 292-312
Author(s): M. J. Gomez-Lechon, M. T. Donato, J. V. Castell, R. Jover
In Vitro Human Hepatocyte-Based Experimental Systems for the Evaluation of Human Drug Metabolism, Drug-Drug Interactions, and Drug Toxicity in Drug Development
Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 11 Year: 2014 Page: 1325-1338
Author(s): Albert P. Li
Higher Throughput Human Hepatocyte Assays for the Evaluation of Time-Dependent Inhibition of CYP3A4
Journal: Drug Metabolism Letters
Volume: 5 Issue: 3 Year: 2011 Page: 183-191
Author(s): Albert P. Li, Utkarsh Doshi
A Novel In vitro Experimental System for the Evaluation of Enteric Drug Metabolism: Cofactor-Supplemented Permeabilized Cryopreserved Human Enterocytes (MetMax⢠Cryopreserved Human Enterocytes)
Journal: Drug Metabolism Letters
Volume: 12 Issue: 2 Year: 2018 Page: 132-137
Author(s): Albert P. Li,Kirsten Amaral,Ming-Chih D. Ho
De-Risking Bio-therapeutics for Possible Drug Interactions Using Cryopreserved Human Hepatocytes
Journal: Current Drug Metabolism
Volume: 13 Issue: 7 Year: 2012 Page: 923-929
Author(s): Shannon Dallas,Carlo Sensenhauser,Ameesha Batheja,Monica Singer,Maria Markowska,Cindy Zakszewski,Rao N.V.S. Mamidi,Michael McMillia,Chao Han,Honghui Zhou,Jose Silva
Application of a Higher Throughput Approach to Derive Apparent Michaelis-Menten Constants of Isoform-Selective P450-Mediated Biotransformation Reactions in Human Hepatocytes
Journal: Drug Metabolism Letters
Volume: 8 Issue: 1 Year: 2014 Page: 2-11
Author(s): Albert P. Li,Kari E. Schlicht
A Novel Plated Hepatocyte Relay Assay (PHRA) for In Vitro Evaluation of Hepatic Metabolic Clearance of Slowly Metabolized Compounds
Journal: Drug Metabolism Letters
Volume: 10 Issue: 1 Year: 2016 Page: 3-15
Author(s): Chi-Chi Peng,Utkarsh Doshi,Chandra Prakash,Albert P. Li