Search Result "compound attrition"
Network Pharmacology: Reigning in Drug Attrition?
Journal: Current Drug Discovery Technologies
Volume: 10 Issue: 2 Year: 2013 Page: 155-159
Author(s): Osama M. Alian,Minjel Shah,Momin Mohammad,Ramzi M. Mohammad
Start Small and Stay Small: Minimizing Attrition in the Clinic with a Focus on CNS Therapeutics
Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1688-1704
Author(s): Vicki Nienaber
Identification and Evaluation of Molecular Properties Related to Preclinical Optimization and Clinical Fate
Journal: Medicinal Chemistry
Volume: 1 Issue: 6 Year: 2005 Page: 649-655
Author(s): J. F. Blake
The New Pre-Preclinical Paradigm: Compound Optimization in Early and Late Phase Drug Discovery
Journal: Current Topics in Medicinal Chemistry
Volume: 1 Issue: 5 Year: 2001 Page: 353-366
Author(s): Gary W. Caldwell, David M. Ritchie, John A. Masucci, William Hageman, Zhengyin Yan
Prediction of Human Intestinal Absorption of Compounds Using Artificial Intelligence Techniques
Journal: Current Drug Discovery Technologies
Volume: 14 Issue: 4 Year: 2017 Page: 244-254
Author(s): Rajnish Kumar,Anju Sharma,Mohammed Haris Siddiqui,Rajesh Kumar Tiwari
New Insights in Drug-Induced Mitochondrial Toxicity
Journal: Current Pharmaceutical Design
Volume: 17 Issue: 2 Year: 2011 Page: 2100-2112
Author(s): Sashi Nadanaciva, Yvonne Will
Multi-Parameter Optimization: Identifying High Quality Compounds with a Balance of Properties
Journal: Current Pharmaceutical Design
Volume: 18 Issue: 9 Year: 2012 Page: 1292-1310
Author(s): Matthew D. Segall
ADME Optimization and Toxicity Assessment in Early- and Late-Phase Drug Discovery
Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 965-980
Author(s): Gary W. Caldwell, Zhengyin Yan, Weimin Tang, Malini Dasgupta, Becki Hasting
Validation of the Neuroinflammation Cycle as a Drug Discovery Target Using Integrative Chemical Biology and Lead Compound Development with an Alzheimers Disease-Related Mouse Model
Journal: Current Alzheimer Research
Volume: 2 Issue: 2 Year: 2005 Page: 197-205
Author(s): Wenhui Hu, Hantamalala Ralay Ranaivo, Jeffrey M. Craft, Linda J. Van Eldik, D. Martin Watterson
Cyclodextrin Inclusion of Medicinal Compounds for Enhancement of their Physicochemical and Biopharmaceutical Properties
Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 25 Year: 2019 Page: 2357-2370
Author(s): Mino R. Caira