Search Result "clearance prediction"


Covariates of Amikacin Clearance in Neonates: The Impact of Postnatal Age on Predictability

Journal: Drug Metabolism Letters
Volume: 2 Issue: 4 Year: 2008 Page: 286-289
Author(s): Karel Allegaert, Isabelle Scheers, Veerle Cossey, Brian J. Anderson

Predicting Clearance in Humans from In Vitro Data

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach

Prediction of Human Hepatic Clearance Using an In Vitro Plated Hepatocyte Clearance Model

Journal: Drug Metabolism Letters
Volume: 3 Issue: 4 Year: 2009 Page: 296-307
Author(s): Piyun Chao, Jeffrey Barminko, Eric Novik, Yi Han, Timothy Maguire, K.-C. Cheng

The Prediction of the Hepatic Clearance of Tanshinone IIA in Rat Liver Subcellular Fractions: Accuracy Improvement

Journal: Current Drug Metabolism
Volume: 9 Issue: 1 Year: 2008 Page: 39-45
Author(s): Guang-Ji Wang, Peng Li, Jing Li, Qian Zhang, Xin Liu, Alexander Khlentzos, Michael S. Roberts

Controversies in Allometric Scaling for Predicting Human Drug Clearance: An Historical Problem and Reflections on What Works and What Does Not

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 340-350
Author(s): Huadong Tang, Michael Mayersohn

Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas

Drug Design Tools - In Silico, In Vitro and In Vivo ADME/PK Prediction and Interpretation: Is PK in Monkey An Essential Part of a Good Human PK Prediction?

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 351-357
Author(s): Natilie A. Hosea

Application of a Convective-Dispersion Model to Predict In Vivo Hepatic Clearance from In Vitro Measurements Utilizing Cryopreserved Human Hepatocytes

Journal: Current Drug Metabolism
Volume: 4 Issue: 5 Year: 2003 Page: 357-369
Author(s): Ryan Niro, James P. Byers, Ronald L. Fournier, Kenneth Bachmann

Atypical Enzyme Kinetics: Their Effect on In Vitro-In Vivo Pharmacokinetic Predictions and Drug Interactions

Journal: Current Drug Metabolism
Volume: 4 Issue: 5 Year: 2003 Page: 341-346
Author(s): Timothy S. Tracy

ARC - Augmented Renal Clearance

Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 1 Year: 2011 Page: 2020-2029
Author(s): Andrew A. Udy, Michael T. Putt, Robert J. Boots, Jeffrey Lipman

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