Search Result "beta secretase and inhibitor"


Memapsin 2 (Beta-Secretase) Inhibitor Drug, between Fantasy and Reality

Journal: Current Alzheimer Research
Volume: 4 Issue: 4 Year: 2007 Page: 418-422
Author(s): Arun K. Ghosh, Geoffrey Bilcer, Lin Hong, Gerald Koelsch, Jordan Tang

Review of Synthesis, Assay, and Prediction of β and γ-secretase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 8 Year: 2012 Page: 828-844
Author(s): Helena Nino,Jose Enrique Rodriguez-Borges,Xerardo Garcia-Mera,Francisco Prado-Prado

Therapeutic Potential of γ -Secretase Inhibitors and Modulators

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 54-61
Author(s): Bruno P. Imbimbo

Computer-Aided Drug Design Applied to Beta and Gamma Secretase Inhibitors-Perspectives for New Alzheimer Disease Therapy

Journal: Current Enzyme Inhibition
Volume: 2 Issue: 4 Year: 2006 Page: 311-328
Author(s): Speranta Avram, Adina L. Milac, Dan F. Mihailescu, Aurelia Dabu, Maria L. Flonta

Inhibitors and Modulators of β- and γ-Secretase

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 4 Year: 2006 Page: 377-392
Author(s): Boris Schmidt, Stefanie Baumann, Hannes A. Braun, Gregor Larbig

Memapsin 2 (Beta-Secretase) Inhibitors: Drug Development

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 121-131
Author(s): Arun K. Ghosh, Nagaswamy Kumaragurubaran, Ling Hong, Gerald Koelsh, Jordan Tang

Review of Bioinformatics and QSAR Studies of β-Secretase Inhibitors

Journal: Current Bioinformatics
Volume: 6 Issue: 1 Year: 2011 Page: 3-15
Author(s): Francisco Prado-Prado, Manuel Escobar-Cubiella, Xerardo Garcia-Mera

Research Article

Berberine Alleviates Amyloid-Beta Pathology in the Brain of APP/PS1 Transgenic Mice via Inhibiting β/γ-Secretases Activity and Enhancing α-Secretases

Journal: Current Alzheimer Research
Volume: 15 Issue: 11 Year: 2018 Page: 1045-1052
Author(s): Zhiyou Cai,Chuanling Wang,Wenbo He,Yi Chen

Beta-Secretase: Structure, Function, and Evolution

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 7 Issue: 3 Year: 2008 Page: 278-294
Author(s): Chitra Venugopal, Christina M. Demos, K. S. Jagannatha Rao, Miguel A. Pappolla, Kumar Sambamurti

Discovery of Notch-Sparing γ-Secretase Inhibitors

Journal: Current Alzheimer Research
Volume: 7 Issue: 3 Year: 2010 Page: 207-209
Author(s): C.E. Augelli-Szafran, H.-X. Wei, D. Lu, J. Zhang, Y. Gu, T. Yang, P. Osenkowski, W. Ye, M.S. Wolfe

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