Search Result "bace knockout mice"


Progress in the Discovery of BACE Inhibitors

Journal: Current Pharmaceutical Design
Volume: 11 Issue: 2 Year: 2005 Page: 3383-3404
Author(s): L. A. Thompson, J. J. Bronson, F. C. Zusi

Human β-secretase (BACE) and BACE Inhibitors: Progress Report

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 6 Year: 2006 Page: 569-578
Author(s): Varghese John

BACE Inhibitors as Potential Drugs for the Treatment of Alzheimers Disease: Focus on Bioactivity

Journal: Recent Patents on CNS Drug Discovery (Discontinued)
Volume: 6 Issue: 2 Year: 2011 Page: 91-106
Author(s): Genevieve Evin, Guillaume Lessene, Simon Wilkins

BACE Inhibitors as Potential Therapeutics for Alzheimers disease

Journal: Recent Patents on CNS Drug Discovery (Discontinued)
Volume: 2 Issue: 3 Year: 2007 Page: 188-199
Author(s): Genevieve Evin, Vijaya B. Kenche

2D QSAR Studies on Series of Human Beta-secretase (BACE-1) Inhibitors

Journal: Medicinal Chemistry
Volume: 10 Issue: 2 Year: 2014 Page: 162-173
Author(s): Daniela Santos Cruz, Marcelo Santos Castilho

BACE Inhibition as a Therapeutic Strategy for Alzheimer`s Disease

Ebook: Frontiers in Clinical Drug Research - Alzheimer Disorders
Volume: 3 Year: 2015
Author(s): Genevieve Evin,Stephanie J. Fuller,Jenny M. Gunnersen
Doi: 10.2174/9781681080680115030006

BACE1 Deficient Mice: Their Role in Drug Target Validation and Implications for Alzheimers Disease Therapies

Journal: Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents
Volume: 3 Issue: 1 Year: 2003 Page: 47-55
Author(s): Robert Vassar

Beta-Secretase: Structure, Function, and Evolution

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 7 Issue: 3 Year: 2008 Page: 278-294
Author(s): Chitra Venugopal, Christina M. Demos, K. S. Jagannatha Rao, Miguel A. Pappolla, Kumar Sambamurti

Review of Synthesis, Biological Assay and QSAR Studies of β-Secretase Inhibitors

Journal: Current Computer-Aided Drug Design
Volume: 7 Issue: 4 Year: 2011 Page: 263-275
Author(s): Helena Nino, Isela Garcia-Pintos, Jose E. Rodriguez-Borges, Manolo Escobar-Cubiella, Xerardo Garcia-Mera, Francisco Prado-Prado

Computational Methods in the Discovery and Design of BACE-1 Inhibitors

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 3 Year: 2012 Page: 6095-6111
Author(s): P. Kacker, G. Bottegoni, A. Cavalli

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