Search Result "alprazolam clearance"


Systematic and Pairwise Analysis of the Effects of Aromatic Halogenation and Trifluoromethyl Substitution on Human Liver Microsomal Clearance

Journal: Drug Metabolism Letters
Volume: 5 Issue: 4 Year: 2011 Page: 232-242
Author(s): Hao Sun, Christopher E. Keefer, Dennis O. Scott

Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas

Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

Journal: Current Drug Metabolism
Volume: 8 Issue: 1 Year: 2007 Page: 33-45
Author(s): Zoe E. Barter, Martin K. Bayliss, Philip H. Beaune, Alan R. Boobis, David J. Carlile, Robert J. Edwards, J. Brian Houston, Brian G. Lake, John C. Lipscomb, Olavi R. Pelkonen, Geoffrey T. Tucke, Amin Rostami-Hodjegan

Research Article

Dispensing Patterns of Anxiolytics and Sedative-Hypnotics: A Feasibility Study Comparing Datasets from a Developed and a Developing Country (Australia and South Africa)

Journal: Current Drug Safety
Volume: 12 Issue: 1 Year: 2017 Page: 57-61
Author(s): Therese Kairuz,Ilse Truter,Laurence Rossato,Alex Pudmenzky

Sex Differences in the Clearance of CYP3A4 Substrates: Exploring Possible Reasons for the Substrate Dependency and Lack of Consensus

Journal: Current Drug Metabolism
Volume: 13 Issue: 6 Year: 2012 Page: 778-786
Author(s): Manoranjenni Chetty, Donald Mattison, Amin Rostami-Hodjegan

Metabolism of Benzodiazepine and Non-Benzodiazepine Anxiolytic-Hypnotic Drugs: an Analytical Point of View

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 815-829
Author(s): Roberto Mandrioli, Laura Mercolini, Maria Augusta Raggi

Maximal Inhibition of Intestinal First-Pass Metabolism as a Pragmatic Indicator of Intestinal Contribution to the Drug-Drug Interactions for CYP3A4 Cleared Drugs

Journal: Current Drug Metabolism
Volume: 8 Issue: 7 Year: 2007 Page: 685-693
Author(s): Aleksandra Galetin, Laura K. Hinton, Howard Burt, R. Scott Obach, J. Brian Houston

Benzodiazepine Metabolism: An Analytical Perspective

Journal: Current Drug Metabolism
Volume: 9 Issue: 8 Year: 2008 Page: 827-844
Author(s): Roberto Mandrioli, Laura Mercolini, Maria Augusta Raggi

Drug Metabolism and Drug Interactions: Application and Clinical Value of In Vitro Models

Journal: Current Drug Metabolism
Volume: 4 Issue: 5 Year: 2003 Page: 423-459
Author(s): Karthik Venkatakrishnan, Lisa L. von Moltke, R. Scott Obach, David J. Greenblatt

Methods for Predicting In Vivo Pharmacokinetics Using Data from In Vitro Assays

Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 940-951
Author(s): J. Brian Houston, Aleksandra Galetin

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