Search Result "allosteric/orthosteric ligands"


Allosteric Modulators for Adenosine Receptors: An Alternative to the Orthosteric Ligands

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 976-992
Author(s): C. La Motta, S. Sartini, M. Morelli, S. Taliani, F. Da Settimo

The Different Ways through Which Specificity Works in Orthosteric and Allosteric Drugs

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 9 Year: 2012 Page: 1311-1316
Author(s): Ruth Nussinov, Chung-Jung Tsai

The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 14-25
Author(s): Brian D. Hudson, Trond Ulven, Graeme Milligan

Druggable Orthosteric and Allosteric Hot Spots to Target Protein-protein Interactions

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 8 Year: 2014 Page: 1293-1301
Author(s): Buyong Ma, Ruth Nussinov

Review Article

Molecular Basis of Modulating Adenosine Receptors Activities

Journal: Current Pharmaceutical Design
Volume: 25 Issue: 7 Year: 2019 Page: 817-831
Author(s): Mohammed Nooraldeen Mahmod Al-Qattan,Mohd Nizam Mordi

Chemical Biology of mGlu4 Receptor Activation: Dogmas, Challenges, Strategies and Opportunities

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 15 Year: 2014 Page: 1755-1770
Author(s): Xinyan Huang,Elena Dale,Robbin M. Brodbeck,Dario Doller

A Hydrazide Linker Strategy for Heterobivalent Compounds as Ortho- and Allosteric Ligands of Acetylcholine-Binding Proteins

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 2 Year: 2011 Page: 2731-2748
Author(s): Paul W. Elsinghorst, Wolfgang Hartig, Daniela Gundisch, Klaus Mohr, Christian Trankle, Michael Gutschow

Allosteric Modulation of G Protein-Coupled Receptors

Journal: Current Pharmaceutical Design
Volume: 10 Issue: 1 Year: 2004 Page: 2003-2013
Author(s): L. T. May, V. A. Avlani, P. M. Sexton, A. Christopoulos

Review Article

Advances in Dopamine D1 Receptor Ligands for Neurotherapeutics

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 16 Year: 2019 Page: 1365-1380
Author(s): Daniel E. Felsing,Manish K. Jain,John A. Allen

Review Article

Recent Advances in the Drug Discovery and Development of Dualsteric/ Bitopic Activators of G Protein-Coupled Receptors

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2019 Page: 2378-2392
Author(s): Bethany A. Reinecke,Huiqun Wang,Yan Zhang

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