Search Result "Time-dependent inhibition (TDI)"
An Examination of IC50 and IC50-Shift Experiments in Assessing Time-Dependent Inhibition of CYP3A4, CYP2D6 and CYP2C9 in Human Liver Microsomes
Journal: Drug Metabolism Letters
Volume: 2 Issue: 1 Year: 2008 Page: 51-59
Author(s): Loren M. Berry, Zhiyang Zhao
Evaluation of Different Approaches to Identifying a Higher Throughput Assay for Time-Dependent Inhibition (TDI)
Journal: Drug Metabolism Letters
Volume: 5 Issue: 2 Year: 2011 Page: 104-113
Author(s): M. Kajbaf, R. Longhi, S. Fontana
Evaluation of Time-Dependent Cytochrome P450 Inhibition in a High-Throughput, Automated Assay: Introducing a Novel Area Under the Curve Shift Approach
Journal: Drug Metabolism Letters
Volume: 6 Issue: 1 Year: 2012 Page: 43-53
Author(s): Sophie Mukadam, Suzanne Tay, Daniel Tran, Leslie Wang, Erlie M. Delarosa, S. Cyrus Khojasteh, Jason S. Halladay, Jane R. Kenny
Higher Throughput Human Hepatocyte Assays for the Evaluation of Time-Dependent Inhibition of CYP3A4
Journal: Drug Metabolism Letters
Volume: 5 Issue: 3 Year: 2011 Page: 183-191
Author(s): Albert P. Li, Utkarsh Doshi
In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities
Journal: Drug Metabolism Letters
Volume: 9 Issue: 1 Year: 2015 Page: 48-62
Author(s): Charles Awortwe,Vamshi K. Manda,Cristina Avonto,Shabana I. Khan,Ikhlas A. Khan,Larry A. Walker,Patrick J. Bouic,Bernd Rosenkranz
In Vitro Cytochrome P450 Inhibition and Induction
Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 928-939
Author(s): Robert L. Walsky, Sherri E. Boldt
Assessment of Cytochrome P450 Enzyme Inhibition and Inactivation in Drug Discovery and Development
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 382-403
Author(s): David O. Nettleton, Heidi J. Einolf
CYP Inhibition-Mediated Drug-Drug Interactions
Journal: Current Enzyme Inhibition
Volume: 6 Issue: 3 Year: 2010 Page: 130-145
Author(s): Karoly Tihanyi, Monika L. Bakk, Eva Hellinger, Monika Vastag
Inhibition of Major Drug Metabolizing CYPs by Common Herbal Medicines used by HIV/AIDS Patients in Africaâ Implications for Herb- Drug Interactions
Journal: Drug Metabolism Letters
Volume: 7 Issue: 2 Year: 2013 Page: 83-95
Author(s): Charles Awortwe,Patrick J. Bouic,Collen M. Masimirembwa,Bernd Rosenkranz
Methods for Predicting In Vivo Pharmacokinetics Using Data from In Vitro Assays
Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 940-951
Author(s): J. Brian Houston, Aleksandra Galetin