Search Result "SXR-humanized mouse"


Quantitative Relationship Between Rifampicin Exposure and Induction of CYP3a11 in SXR Humanized Mice: Extrapolation to Human CYP3A4 Induction Potential

Journal: Drug Metabolism Letters
Volume: 2 Issue: 3 Year: 2008 Page: 169-175
Author(s): Sean Kim, Devin Pray, Ming Zheng, Danial G. Morgan, Jenifer G. Pizzano, Mary E. Zoeckler, Anjaneya Chimalakonda, Michael W. Sinz

Applications and Limitations of Genetically Modified Mouse Models in Drug Discovery and Development

Journal: Current Drug Metabolism
Volume: 9 Issue: 5 Year: 2008 Page: 419-438
Author(s): Jiunn H. Lin

Use of Mouse Models to Evaluate Roles of Nuclear Receptors and their Ligands in the Pathogenesis and Treatment of Atherosclerosis

Journal: Current Drug Targets
Volume: 8 Issue: 1 Year: 2007 Page: 1273-1287
Author(s): A. C. Li, C. K. Glass

Troglitazone Thiol Adduct Formation in Human Liver Microsomes: Enzyme Knietics and Reaction Phenotyping

Journal: Drug Metabolism Letters
Volume: 2 Issue: 3 Year: 2008 Page: 184-189
Author(s): Jinping Gan, Qinling Qu, Bing He, Wen C. Shyu, A. David Rodrigues, Kan He

Animal Models of Xenobiotic Receptors

Journal: Current Drug Metabolism
Volume: 6 Issue: 4 Year: 2005 Page: 341-355
Author(s): G. Dai, Y.- J.Y. Wan

Orphan Nuclear Receptors, Excellent Targets of Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 9 Year: 2006 Page: 683-689
Author(s): Yanhong Shi

A Nuclear Receptor-Mediated Xenobiotic Response and Its Implication in Drug Metabolism and Host Protection

Journal: Current Drug Metabolism
Volume: 4 Issue: 1 Year: 2003 Page: 59-72
Author(s): J. Sonoda, J. M. Rosenfeld, L. Xu, R. M. Evans, W. Xie

Induction of Cytochromes P450

Journal: Current Drug Metabolism
Volume: 2 Issue: 2 Year: 2001 Page: 139-147
Author(s): Erin G. Schuetz

The Entero-Hepatic Nuclear Receptors Integrate Cholesterol, Lipid, and Bile Acid Homeostasis

Journal: Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents
Volume: 2 Issue: 1 Year: 2002 Page: 56-64
Author(s): Elisabeth Fayard, Kristina Schoonjans, Johan Auwerx

Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily

Journal: Current Drug Metabolism
Volume: 14 Issue: 10 Year: 2013 Page: 1059-1069
Author(s): Tomas Smutny,Sridhar Mani,Petr Pavek

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