Search Result "Phosphoinositide-Dependent Kinase-1 (PDK1)"
Targeting PDK1 in Cancer
Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2763-2769
Author(s): C. Raimondi, M. Falasca
Investigation of Binding Characteristics of Phosphoinositide-dependent Kinase-1 (PDK1) Co-crystallized Ligands Through Virtual Pharmacophore Modeling Leading to Novel Anti-PDK1 Hits
Journal: Medicinal Chemistry
Volume: 16 Issue: 7 Year: 2020 Page: 860-880
Author(s): Iman A. Mansi,Mahmoud A. Al-Sha'er,Nizar M. Mhaidat,Mutasem O. Taha,Rand Shahin
A New Molecular Target of Insulin Action: Regulating the Pivotal PDK1
Journal: Current Drug Targets - Immune, Endocrine & Metabolic Disorders
Volume: 1 Issue: 3 Year: 2001 Page: 209-221
Author(s): K.L.R. Wick, F. Liu
Ligand Based Pharmacophore Modeling Followed by Biological Screening Lead to Discovery of Novel PDK1 Inhibitors as Anticancer Agents
Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 20 Issue: 4 Year: 2020 Page: 476-485
Author(s): Iman Mansi,Mahmoud A. Al-Sha'er,Nizar Mhaidat,Mutasem Taha
PDK1 Inhibitor GSK-470 Exhibits Potent Anticancer Activity in a Pheochromocytoma PC12 Cell Tumor Model via Akt/mTOR Pathway
Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 20 Issue: 7 Year: 2020 Page: 828-833
Author(s): Xiaohua Zhang,Shan Zhong
Efficient Identification of Novel Leads by Dynamic Focused Screening: PDK1 Case Study
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 1 Year: 2010 Page: 16-26
Author(s): Dongyu Sun, Joon Jung, Thomas S. Rush III, Zangwei Xu, Michael J. Weber, Ekaterina Bobkova, Alan Northrup, Ilona Kariv
PI3K/Akt/mTOR Pathway Inhibitors in Cancer: A Perspective on Clinical Progress
Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 4326-4341
Author(s): P. Wu, Y.-Z. Hu
Selective Cyclooxygenase-2 Inhibitors for Malignant Glioma Therapy: Molecular Targets Beyond COX-2
Ebook: Advances in Anticancer Agents in Medicinal Chemistry
Volume: 1 Year: 2013
Author(s): Axel H. Schönthal
Doi: 10.2174/9781608054930113010011
Recent Progress in Signal Transduction Research of the Angiotensin II Type-1 Receptor: Protein Kinases, Vascular Dysfunction and Structural Requirement
Journal: Current Medicinal Chemistry - Cardiovascular & Hematological Agents
Volume: 3 Issue: 4 Year: 2005 Page: 305-322
Author(s): H. Suzuki, E. D. Motley, G. D. Frank, H. Utsunomiya, S. Eguchi
Regulation and Importance of the PI3K/Akt/mTOR Signaling Pathway in Hematologic Malignancies
Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 9 Issue: 9 Year: 2009 Page: 1024-1038
Author(s): Kiyotaka Kawauchi, Toshie Ogasawara, Masako Yasuyama, Kuniaki Otsuka, Osamu Yamada