Search Result "PI3Kα"


Research Article

Molecular Docking Studies of Novel Thiosemicarbazone-based Indoles as Potential PI3Kα Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 11 Year: 2017 Page: 1252-1258
Author(s): Dima A. Sabbah,Kamal Sweidan

Computational Medicinal Chemistry to Design Novel Phosphoinositide 3- Kinase (PI3K) Alpha Inhibitors in View of Cancer

Journal: Current Bioactive Compounds
Volume: 10 Issue: 3 Year: 2014 Page: 147-157
Author(s): Lorane I. Hage-Melim,Cleydson B.R. Santos,Joao G. Poiani,Miguel de Menezes Vaidergom,Eduardo S. Manzolli,Carlos H.T. de Paula da Silva

Review Article

Triggering PIK3CA Mutations in PI3K/Akt/mTOR Axis: Exploration of Newer Inhibitors and Rational Preventive Strategies

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 39 Year: 2016 Page: 6039-6054
Author(s): Vivek Asati,Sanjay K. Bharti,Debarshi Kar Mahapatra,Vikas Asati,Ashok K. Budhwani

Oxygen-independent Regulation of HIF-1: Novel Involvement of PI3K/ AKT/mTOR Pathway in Cancer

Journal: Current Cancer Drug Targets
Volume: 13 Issue: 3 Year: 2013 Page: 245-251
Author(s): Faton Agani, Bing-Hua Jiang

Altered Calmodulin Degradation and Signaling in Non-Neuronal Cells from Alzheimer’s Disease Patients

Journal: Current Alzheimer Research
Volume: 9 Issue: 3 Year: 2012 Page: 267-277
Author(s): Noemi Esteras,Ursula Munoz,Carolina Alquezar,Fernando Bartolome,Felix Bermejo-Pareja,Angeles Martin-Requero

Novel Agents, Combinations and Sequences for the Treatment of Advanced Renal Cell Carcinoma: When is the Revolution Coming?

Journal: Current Cancer Drug Targets
Volume: 13 Issue: 3 Year: 2013 Page: 313-325
Author(s): Matteo Santoni, Mimma Rizzo, Luciano Burattini, Rossana Berardi, Giacomo Carteni, Stefano Cascinu

Research Article

Phosphatidylinositol 3-kinase Glu545Lys and His1047Tyr Mutations are not Associated with T2D

Journal: Current Diabetes Reviews
Volume: 16 Issue: 8 Year: 2020 Page: 881-888
Author(s): Imadeldin Elfaki,Rashid Mir,Faisel M. Abu-Duhier,Roaid Khan,Mohammed Sakran

Naringin Inhibits TNF-α Induced Oxidative Stress and Inflammatory Response in HUVECs via Nox4/NF-κ B and PI3K/Akt Pathways

Journal: Current Pharmaceutical Biotechnology
Volume: 15 Issue: 12 Year: 2014 Page: 1173-1182
Author(s): Wenshuang Li,Changyuan Wang,Jinyong Peng,Jing Liang,Yue Jin,Qi Liu,Qiang Meng,Kexin Liu,Huijun Sun

Review Article

Advances in Medicinal Chemistry of Estrogen-related Receptor Alpha(ERRα) Inverse Agonists

Journal: Current Topics in Medicinal Chemistry
Volume: 23 Issue: 20 Year: 2023 Page: 1952-1963
Author(s):

Research Article

Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents

Journal: Medicinal Chemistry
Volume: 15 Issue: 4 Year: 2019 Page: 417-429
Author(s): Dima A. Sabbah,Ameerah H. Ibrahim,Wamidh H. Talib,Khalid M. Alqaisi,Kamal Sweidan,Sanaa K. Bardaweel,Ghassan A. Sheikha,Haizhen A. Zhong,Eveen Al-Shalabi,Reema A. Khalaf,Mohammad S. Mubarak

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