Search Result "PDE5 Catalytic Domain"


Crystal Structures of Phosphodiesterases and Implications on Substrate Specificity and Inhibitor Selectivity

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 4 Year: 2007 Page: 391-403
Author(s): Hengming Ke, Huanchen Wang

PDE5 Inhibitors: In Vitro and In Vivo Pharmacological Profile

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 3 Year: 2009 Page: 3464-3475
Author(s): D. Kouvelas, A. Goulas, G. Papazisis, C. Sardeli, C. Pourzitaki

The Novel Functions of cGMP-Specific Phosphodiesterase 5 and its Inhibitors in Carcinoma Cells and Pulmonary/Cardiovascular Vessels

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 4 Year: 2007 Page: 437-454
Author(s): Bing Zhu, Samuel J Strada

Phosphodiesterase 5 Inhibitors - Drug Design and Differentiation Based on Selectivity, Pharmacokinetic and Efficacy Profiles

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 2 Year: 2006 Page: 3459-3465
Author(s): Claudiu T. Supuran, Antonio Mastrolorenzo, Giuseppe Barbaro, Andrea Scozzafava

Expression, Distribution and Regulation of Phosphodiesterase 5

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 2 Year: 2006 Page: 3439-3457
Author(s): Ching-Shwun Lin, Guiting Lin, Zhong-Cheng Xin, Tom F. Lue

Cyclic Nucleotide Phosphodiesterases (PDE) and Peptide Motifs

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 9 Year: 2010 Page: 1114-1125
Author(s): Therese Keravis, Claire Lugnier

Design of Second Generation Phosphodiesterase 5 Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 4 Year: 2007 Page: 405-419
Author(s): Michael J. Palmer, Andrew S. Bell, David N. A. Fox, David G. Brown

Non-Covalent Binding of Disodium Disuccinate Astaxanthin to the Catalytic Site of Phosphodiesterase 5A: A Molecular Modeling Study

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 2 Year: 2007 Page: 128-136
Author(s): Eszter Hazai, Zsolt Bikadi, Ferenc Zsila, Samuel F. Lockwood

Phosphodiesterase 5 Inhibitors in the Treatment of Erectile Dysfunction

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 2 Year: 2006 Page: 3467-3484
Author(s): Antonio Aversa, Roberto Bruzziches, Marcello Pili, Giovanni Spera

Phosphodiesterase Inhibitors as Potential Cognition Enhancing Agents

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 2 Year: 2010 Page: 222-230
Author(s): Christopher J. Schmidt

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