Search Result "Microsomal stability"


Applications of High Throughput Microsomal Stability Assay in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 6 Year: 2008 Page: 469-476
Author(s): Li Di, Edward H. Kerns, Xuewen JoAnn Ma, Youping Huang, Guy T. Carter

Metabolic Stability Screen for Drug Discovery Using Cassette Analysis and Column Switching

Journal: Drug Metabolism Letters
Volume: 1 Issue: 1 Year: 2007 Page: 67-72
Author(s): Jason S. Halladay, Susan Wong, Sharmin M. Jaffer, Achintya K. Sinhababu, S. Cyrus Khojasteh-Bakht

In Vitro Microsomal Hepatic Metabolism of Antiasthmatic Prototype LASSBio-448

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 11 Year: 2014 Page: 1388-1398
Author(s): Isabelle Karine Costa Nunes,Luzineide Wanderley Tinoco,Helvecio Martins-Junior,Claudia Rezende,Eliezer J. Barreiro,Lidia Moreira Lima

Metabolism of Dietary Flavonoids in Liver Microsomes

Journal: Current Drug Metabolism
Volume: 14 Issue: 4 Year: 2013 Page: 381-391
Author(s): Jianbo Xiao, Petra Hogger

Research Article

Synthesis, Aqueous Solubility, Metabolic Stability and Pharmacological Profile of Simplified Urea Derivatives

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 7 Year: 2018 Page: 766-777
Author(s): Raquel de Oliveira Lopes,Marina Amaral Alves,Roberta Olmo Pinheiro,Cristina Setim Freitas,Fernando Q. Cunha,Eliezer J. Barreiro,Lídia Moreira Lima

Systematic and Pairwise Analysis of the Effects of Aromatic Halogenation and Trifluoromethyl Substitution on Human Liver Microsomal Clearance

Journal: Drug Metabolism Letters
Volume: 5 Issue: 4 Year: 2011 Page: 232-242
Author(s): Hao Sun, Christopher E. Keefer, Dennis O. Scott

Future Challenges for Microsomal Transport Protein Inhibitors

Journal: Current Vascular Pharmacology
Volume: 7 Issue: 3 Year: 2009 Page: 277-286
Author(s): Anthony S. Wierzbicki, Tim Hardman, William T. Prince

Solution Stability - Plasma, Gastrointestinal, Bioassay

Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 860-868
Author(s): Li Di, Edward H. Kerns

General Research Article

Assessment of the Physicochemical Properties and Stability for Pharmacokinetic Prediction of Pyrazinoic Acid Derivatives

Journal: Current Drug Metabolism
Volume: 21 Issue: 9 Year: 2020 Page: 714-721
Author(s): Taísa Busaranho Franchin,Bruna Cristina Ulian Silva,Rone Aparecido DeGrandis,Michelle Fidelis Corrêa,Cecília Maria Simões de Queiroz Aranha,Joáo Paulo S. Fernandes,Michel Leandro Campos,Rosângela Gonçalves Peccinini

Research Article

Metabolic Analysis of Triptolide Microspheres in Human, Dog, Rabbit and Rat Liver Microsomes with UPLC-MS/MS Method

Journal: Current Pharmaceutical Analysis
Volume: 17 Issue: 9 Year: 2021 Page: 1206-1217
Author(s): Li Juan Wang,Yan Liu,Rui Li,Dong Xian He

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