Search Result "Metabolism-based inhibitor (MBI)"
Enzyme Kinetics for Clinically Relevant CYP Inhibition
Journal: Current Drug Metabolism
Volume: 6 Issue: 3 Year: 2005 Page: 241-257
Author(s): Zhi-Yi Zhang, Y. Nancy Wong
Mechanism-Based Inhibitors from Phytomedicine: Risks of Hepatotoxicity and their Potential Hepatotoxic Substructures
Journal: Current Drug Metabolism
Volume: 17 Issue: 10 Year: 2016 Page: 971-991
Author(s): Lili Wang,Xin He,Chunhuan Jin,Gregory Ondieki
Cytochrome P450 Turnover: Regulation of Synthesis and Degradation, Methods for Determining Rates, and Implications for the Prediction of Drug Interactions
Journal: Current Drug Metabolism
Volume: 9 Issue: 5 Year: 2008 Page: 384-393
Author(s): Jiansong Yang, Mingxiang Liao, Magang Shou, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker, Amin Rostami-Hodjegan
A Critical Evaluation of the Experimental Design of Studies of Mechanism Based Enzyme Inhibition, with Implications for In Vitro-In Vivo Extrapolation
Journal: Current Drug Metabolism
Volume: 7 Issue: 3 Year: 2006 Page: 315-334
Author(s): F. Ghanbari, K. Rowland-Yeo, J. C. Bloomer, S. E. Clarke, M. S. Lennard, G. T. Tucker, A. Rostami-Hodjegan
Integrating In Vitro Kinetic Data from Compounds Exhibiting Induction, Reversible Inhibition and Mechanism-Based Inactivation: In Vitro Study Design
Journal: Current Drug Metabolism
Volume: 5 Issue: 2 Year: 2004 Page: 141-146
Author(s): Donavon J. McConn, Zhiyang Zhao
Emerging In Vitro Tools to Evaluate Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions
Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 3 Year: 2010 Page: 199-222
Author(s): Cormac Concannon, Desmond A. Hennelly, Simon Noott, Dipak K. Sarker, Chuang Lu, Mingxiang Liao, Lawrence Cohen, Cindy Q. Xia
Inactivation of CYP3A4 by Benzbromarone in Human Liver Microsomes
Journal: Drug Metabolism Letters
Volume: 10 Issue: 1 Year: 2016 Page: 16-21
Author(s): Yasuhiro Masubuchi,Shinji Kondo
Enzymes of the Trypanothione Metabolism as Targets for Antitrypanosomal Drug Development
Journal: Current Topics in Medicinal Chemistry
Volume: 2 Issue: 1 Year: 2002 Page: 1239-1259
Author(s): Armin Schmidt, R. Luise Krauth-Siegel
Induction and Inhibition of Drug Metabolizing Enzymes
Ebook: Solubility, Delivery and ADME Problems of Drugs and Drug-Candidates
Volume: 1 Year: 2011
Author(s): Karoly Tihanyi
Doi: 10.2174/978160805120511101010117
CYP Inhibition-Mediated Drug-Drug Interactions
Journal: Current Enzyme Inhibition
Volume: 6 Issue: 3 Year: 2010 Page: 130-145
Author(s): Karoly Tihanyi, Monika L. Bakk, Eva Hellinger, Monika Vastag