Search Result "MPPGL"
Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver
Journal: Current Drug Metabolism
Volume: 8 Issue: 1 Year: 2007 Page: 33-45
Author(s): Zoe E. Barter, Martin K. Bayliss, Philip H. Beaune, Alan R. Boobis, David J. Carlile, Robert J. Edwards, J. Brian Houston, Brian G. Lake, John C. Lipscomb, Olavi R. Pelkonen, Geoffrey T. Tucke, Amin Rostami-Hodjegan
Predicting Pediatric Drug Disposition-Present and Future Directions of Pediatric Physiologically-Based Pharmacokinetics
Journal: Drug Metabolism Letters
Volume: 9 Issue: 2 Year: 2015 Page: 80-87
Author(s): Shogo John Miyagi,Janel R. Long-Boyle
In Vitro-In Vivo Correlation Using In Silico Modeling of Physiological Properties, Metabolites, and Intestinal Metabolism
Journal: Current Drug Metabolism
Volume: 18 Issue: 11 Year: 2017 Page: 973-982
Author(s): Sung-min Choi,Chin-Yang Kang,Beom-Jin Lee,Jun-Bom Park
Methodologies for Investigating Drug Metabolism at the Early Drug Discovery Stage: Prediction of Hepatic Drug Clearance and P450 Contribution
Journal: Current Drug Metabolism
Volume: 11 Issue: 8 Year: 2010 Page: 678-685
Author(s): Chie Emoto, Norie Murayama, Amin Rostami-Hodjegan, Hiroshi Yamazaki
Ontogeny of Hepatic Glucuronidation; Methods and Results
Journal: Current Drug Metabolism
Volume: 13 Issue: 6 Year: 2012 Page: 728-743
Author(s): Elke H.J. Krekels, Meindert Danhof, Dick Tibboel, Catherijne A.J. Knibbe
Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model
Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas
Why We Need Proper PBPK Models to Examine Intestine and Liver Oral Drug Absorption
Journal: Current Drug Metabolism
Volume: 14 Issue: 1 Year: 2013 Page: 57-79
Author(s): Edwin C.Y. Chow,K. Sandy Pang
Sex Differences in the Clearance of CYP3A4 Substrates: Exploring Possible Reasons for the Substrate Dependency and Lack of Consensus
Journal: Current Drug Metabolism
Volume: 13 Issue: 6 Year: 2012 Page: 778-786
Author(s): Manoranjenni Chetty, Donald Mattison, Amin Rostami-Hodjegan