Search Result "Lipinski's Rule of Five"


Research Article

Withania somnifera Phytochemicals Confer Neuroprotection by Inhibition of the Catalytic Domain of Human Matrix Metalloproteinase-9

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 6 Year: 2017 Page: 718-726
Author(s): Gaurav Kumar,Pankaj Paliwal,Ranjana Patnaik

Research Article

New SARS-CoV-2 Mpro Inhibitor by Ascorbic Acid: Design, MolecularDocking, Lipinski’s Rule and ADMET Analysis

Journal: Coronaviruses
Volume: 5 Issue: 1 Year: 2024 Page: 13-52
Author(s): Abdulrahman Salman Alazmi

General Research Article

Structure-based Virtual Screening, Molecular Docking, MolecularDynamics Simulation, and Metabolic Reactivity Studies ofQuinazoline Derivatives for their Anti-EGFR Activity AgainstTumor Angiogenesis

Journal: Current Medicinal Chemistry
Volume: 31 Issue: 5 Year: 2024 Page: 595-619
Author(s): Altaf Ahmad Shah,Manoj Kumar Yadav,Mohammad Amjad Kamal

Design, Synthesis and Evaluation of Unique 2,4,5-triaryl Imidazole Derivatives as Novel Potent Aspartic Protease Inhibitors

Journal: Medicinal Chemistry
Volume: 8 Issue: 3 Year: 2012 Page: 428-435
Author(s): Mohd Sajid Khan,Salman Akhtar,S. A. Siddiqui,M. S. Siddiqui,K. V. Srinivasan,J. M. Arif

Virtual Screening for Novel Staphylococcus Aureus NorA Efflux Pump Inhibitors From Natural Products

Journal: Medicinal Chemistry
Volume: 11 Issue: 2 Year: 2015 Page: 135-155
Author(s): Khac-Minh Thai,Trieu-Du Ngo,Thien-Vy Phan,Thanh-Dao Tran,Ngoc-Vinh Nguyen,Thien-Hai Nguyen,Minh-Tri Le

Review Article

The use of Sulfonamide Derivatives in the Treatment of Trypanosomatid Parasites including Trypanosoma cruzi, Trypanosoma brucei, and Leishmania ssp

Journal: Medicinal Chemistry
Volume: 16 Issue: 1 Year: 2020 Page: 24-38
Author(s): Cauê B. Scarim,Rafael C. Chelucci,Jean L. dos Santos,Chung M. Chin

Research Article

Design, Synthesis, In vitro and In silico Evaluation of New Hydrazonebased Antitumor Agents as Potent Akt Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 11 Year: 2020 Page: 1380-1392
Author(s): Emine Merve Güngör,Mehlika Dilek Altıntop,Belgin Sever,Gülşen Akalın Çiftçi

Research Article

Molecular Docking of Phytochemical Compounds of Momordica charantiaas Potential Inhibitors against SARS-CoV-2

Journal: Infectious Disorders - Drug Targets
Volume: 22 Issue: 3 Year: 2022 Page: 57-63
Author(s): Yayu Mulsiani Evary,Arie Ariezandi Kurnianto,Rangga Meidianto Asri

Research Article

In silico Evaluation and Neuroprotective Effect of Jasmonic Acid on SleepDeprivation Induced Alzheimer’s in Zebrafish

Journal: Current Bioactive Compounds
Volume: 19 Issue: 7 Year: 2023 Page: 69-80
Author(s): Vijay Babu Anandan

Research Article

Synthesis, In silico Molecular Docking and Pharmacokinetic Studies, In vitro Antimycobacterial and Antimicrobial Studies of New Imidozolones Clubbed with Thiazolidinedione

Journal: Current Computer-Aided Drug Design
Volume: 14 Issue: 4 Year: 2018 Page: 269-283
Author(s): Imran. H. Khan,Navin B. Patel,Vatsal M. Patel

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