Search Result "IC50 values"


Impact of Impurities on IC50 Values of P450 Inhibitors

Journal: Drug Metabolism Letters
Volume: 5 Issue: 3 Year: 2011 Page: 156-162
Author(s): Zeqi Huang

An Examination of IC50 and IC50-Shift Experiments in Assessing Time-Dependent Inhibition of CYP3A4, CYP2D6 and CYP2C9 in Human Liver Microsomes

Journal: Drug Metabolism Letters
Volume: 2 Issue: 1 Year: 2008 Page: 51-59
Author(s): Loren M. Berry, Zhiyang Zhao

Research Article

Molecular Docking and Structure Activity Relationship Studies of NSAIDs. What do they Reveal about IC50?

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 8 Year: 2017 Page: 949-958
Author(s): Chrysoula Mikra,Georgios Rossos,Sotirios K. Hadjikakou,Nikolaos Kourkoumelis

Research Article

Studies on the IC50 of Metabolically Stable 1-(3,3-diphenylpropyl)- piperidinyl Amides and Ureas as Human CCR5 Receptor Antagonists Based on QSAR

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 8 Year: 2020 Page: 1036-1046
Author(s): Yutao Zhao,Xiaoqian Liu,Jing Ouyang,Yan Wang,Shanyu Xu,Dongdong Tian,Hongzong Si

Review Article

Current Status and Future Perspective for Research on Medicinal Plants with Anticancerous Activity and Minimum Cytotoxic Value

Journal: Current Drug Targets
Volume: 20 Issue: 12 Year: 2019 Page: 1227-1243
Author(s): Hina Qamar,Sumbul Rehman,D.K. Chauhan

Review Article

Synthesis Strategies and Medicinal Value of Pyrrole and its FusedHeterocyclic Compounds

Journal: Medicinal Chemistry
Volume: 18 Issue: 10 Year: 2022 Page: 1013-1043
Author(s): Samar Said Fatahala,Mosaad Sayed Mohamed,Jaqueline Youssef Sabry,Yara Esam El-Deen Mansour

Identification of LOGP Values and Electronegativities As Structural Insights to Model Inhibitory Activity of HIV-1 Capsid Inhibitors - A SVM and MLR Aided QSAR Studies

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 16 Year: 2012 Page: 1763-1774
Author(s): Nishant Sharma,K.R. Ethiraj,Mukesh Yadav,Anuraj Nayarisseri S,Mona Chaurasiya,Raju Naik Vankudavath,K. Rajender Rao

Qualitative and Quantitative Assessment of Drug-Drug Interaction Potential in Man, Based on Ki, IC50 and Inhibitor Concentration

Journal: Current Drug Metabolism
Volume: 5 Issue: 2 Year: 2004 Page: 147-156
Author(s): N. Blanchard, L. Richert, P. Coassolo, T. Lave

Selective Neuronal Nitric Oxide Synthase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 7 Year: 2005 Page: 603-624
Author(s): Erik P. Erdal, Elizabeth A. Litzinger, Jiwon Seo, Yaoqiu Zhu, Haitao Ji, Richard B. Silverman

Pyridinium Oxime Reactivators of Cholinesterase Inhibited by Diisopropyl- Fluorophosphate (DFP): Predictive Value of In-Vitro Testing for In-Vivo Efficacy

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1328-1342
Author(s): G. A. Petroianu, D. E. Lorke

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