Search Result "IC50 9 nM"


Impact of Impurities on IC50 Values of P450 Inhibitors

Journal: Drug Metabolism Letters
Volume: 5 Issue: 3 Year: 2011 Page: 156-162
Author(s): Zeqi Huang

pH-Gradient Incorporation of 9-Nitrocamptothecin in PEGylated Liposomes: Formulation Properties and Efficacy In Vitro and In Vivo

Journal: Pharmaceutical Nanotechnology
Volume: 1 Issue: 2 Year: 2013 Page: 115-125
Author(s): Shuang Chang,Li Xie,Hong Ding,Yu Nie,Yao Wu,Bin He,Zhongwei Gu

Research Article

The Effects of 1,3,5-trisubstituted Indole Derivatives on Cell Growth, Apoptosis and MMP-2/9 mRNA Expression of MCF-7 Human Breast Cancer Cells

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 17 Issue: 5 Year: 2017 Page: 762-767
Author(s): Filiz Bakar,Zuhal Kilic-Kurt,Mehmet Gokhan Caglayan,Sureyya Olgen

Potent, Nonpeptide Inhibitors of Human Mast Cell Tryptase. 2. Investigation of the Carboxamide Portion of Spirocyclic Piperidine Amides

Journal: Letters in Drug Design & Discovery
Volume: 5 Issue: 2 Year: 2008 Page: 116-121
Author(s): Michael J. Costanzo, Stephen C. Yabut, Han-Cheng Zhang, Kimberley B. White, Yuanping Wang, Lisa K. Minor, Brett A. Tounge, Alexander N. Barnakov, Frank Lewandowski, Cynthia Milligan, John C. Spurlino, Bruce E. Maryanoff

Synthesis and Biological Evaluation of 2-, 3-, and 4-Acylaminocinnamyl-Nhydroxyamides as Novel Synthetic HDAC Inhibitors

Journal: Medicinal Chemistry
Volume: 1 Issue: 3 Year: 2005 Page: 245-254
Author(s): A. Mai, S. Massa, R. Pezzi, S. Valente, P. Loidl, G. Brosch

Review Article

Progress and Development of C-3, C-6, and N-9 Positions Substituted CarbazoleIntegrated Molecular Hybrid Molecules as Potential AnticancerAgents

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 21 Issue: 19 Year: 2021 Page: 2929-2956
Author(s): Pratibha Mehta Luthra,Nitin Kumar

N-Aroylated Isatins: Antiglycation Activity

Journal: Letters in Drug Design & Discovery
Volume: 7 Issue: 3 Year: 2010 Page: 188-193
Author(s): Khalid Mohammed Khan, Uzma Rasool Mughal, Ambreen Khan, Farzana Naz, Shahnaz Perveen, M. Iqbal Choudhary

Research Article

Synthesis and Anticancer Activity of 9-O-Pyrazole Alkyl Substituted Berberine Derivatives

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 11 Year: 2018 Page: 1639-1648
Author(s): Daipeng Xiao,Fen He,Dongming Peng,Min Zou,Junying Peng,Pan Liu,Yanfei Liu,Zhenbao Liu

Fungal Metabolites as Potent Protein Kinase Inhibitors: Identification of a Novel Metabolite and Novel Activities of Known Metabolites

Journal: Letters in Drug Design & Discovery
Volume: 1 Issue: 1 Year: 2004 Page: 24-29
Author(s): Masayoshi Oyama, Zhihong Xu, Kuo-Hsiung Lee, Timothy D. Spitzer, Peter Kitrinos, Octerloney B. McDonald, Rosie R.J. Jones, Edward P. Garvey

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