Search Result "Human drug metabolites"


The In Silico Prediction of Human-Specific Metabolites from Hepatotoxic Drugs

Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 3 Year: 2010 Page: 170-187
Author(s): Ravouru Nagaraju, Ande Penchala Prathusha, Rajesh Kaza, Koganti Bharathi, Luis G. Valerio, Anthony Long

Mini-Review Article

Metabolite Identification in the Preclinical and Clinical Phase of Drug Development

Journal: Current Drug Metabolism
Volume: 22 Issue: 11 Year: 2021 Page: 838-857
Author(s): Yali Wu,Lulu Pan,Zhendong Chen,Yuandong Zheng,Xingxing Diao,Dafang Zhong

Addressing MIST (Metabolites in Safety Testing): Bioanalytical Approaches to Address Metabolite Exposures in Humans and Animals

Journal: Current Drug Metabolism
Volume: 12 Issue: 6 Year: 2011 Page: 578-586
Author(s): Hongying Gao, R. Scott Obach

Are Circulating Metabolites Important in Pharmacokinetic Drug-Drug Interactions? A Retroanalysis of Clinical Data

Journal: Current Drug Metabolism
Volume: 15 Issue: 8 Year: 2014 Page: 767-790
Author(s): Yuan-Sheng Zhao,Feng Chen,Li Li

Characterization and Preclinical Perspectives of Organic Small Molecule Drug Metabolites in Drug-drug Interactions

Journal: Current Organic Chemistry
Volume: 20 Issue: 17 Year: 2016 Page: 1827-1834
Author(s): Liqian Gao,Jun Chen,Yi Hu,Hongyan Sun,Yong Siang Ong,Jingxin Zhang,Zhifang Chai,Su Seong Lee

General Review Article

Gut Mycobiota and Fungal Metabolites in Human Homeostasis

Journal: Current Drug Targets
Volume: 20 Issue: 2 Year: 2019 Page: 232-240
Author(s): Izabella Mogilnicka,Marcin Ufnal

Enantioselective Analysis of Antimalarial Drugs and their Metabolites

Journal: Current Pharmaceutical Analysis
Volume: 6 Issue: 1 Year: 2010 Page: 15-29
Author(s): Igor R. Santos Magalhaes, Pierina S. Bonato

Are Chemically Reactive Metabolites Responsible for Adverse Reactions to Drugs?

Journal: Current Drug Metabolism
Volume: 3 Issue: 4 Year: 2002 Page: 351-366
Author(s): D. P. Williams, N. R. Kitteringham, D. J. Naisbitt, M. Pirmohamed, D. A. Smith, B. K. Park

Isotopic Labeling of Metabolites in Drug Discovery Applications

Journal: Current Drug Metabolism
Volume: 13 Issue: 9 Year: 2012 Page: 1213-1225
Author(s): Jacobo Iglesias,Lekha Sleno,Dietrich A. Volmer

Drug Metabolite Generation Using a Laboratory Evolved NADPH Independent Cytochrome P450: Application of in vitro and in silico Approaches

Journal: Drug Metabolism Letters
Volume: 7 Issue: 1 Year: 2013 Page: 68-77
Author(s): Nyaradzo T. L. Chigorimbo-Murefu,Mathew Njoroge,Stefan Louw,Grace Mugumbate,Kelly Chibale

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