Search Result "Hit expansion"


Lead Generation - Enhancing the Success of Drug Discovery by Investing in the Hit to Lead Process

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 1 Year: 2003 Page: 51-66
Author(s): Alexander Alanine, Matthias Nettekoven, Edward Roberts, Andrew W. Thomas

Clonal Expansion of Mitochondrial DNA Deletions and the Progression of Multiple Sclerosis

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 11 Issue: 5 Year: 2012 Page: 589-597
Author(s): Graham R. Campbell,Don J. Mahad

A Collaborative Hit-to-Lead Investigation Leveraging Medicinal Chemistry Expertise with High Throughput Library Design, Synthesis and Purification Capabilities

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 123-130
Author(s): X. Yang, D. Parker, L. Whitehead, N. S. Ryder, B. Weidmann, M. Stabile-Harris, D. Kizer, M. McKinnon, A. Smellie, D. Powers

Proteolytic Cleavage of Notch: “HIT and RUN”

Journal: Current Molecular Medicine
Volume: 11 Issue: 4 Year: 2011 Page: 255-269
Author(s): G. van Tetering, M. Vooijs

Opportunities Offered by Fragment-Based Drug Design in Antibiotic Development

Ebook: Frontiers in Anti-Infective Drug Discovery
Volume: 8 Year: 2020
Author(s): Sanjay Yapabandara,Lorna Wilkinson-White,Sandro Ataide,Ann H. Kwan
Doi: 10.2174/9789811412387120080005

Rational Design Approaches to Chemical Libraries for Hit Identification

Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 1 Year: 2006 Page: 49-65
Author(s): Konstantin V. Balakin, Alexander V. Kozintsev, Alex S. Kiselyov, Nikolay P. Savchuk

Coupling Two Rotary-Type Actuators

Ebook: Semi-rotary and Linear Actuators for Compressed Air Energy Storage and Energy Efficient Pneumatic Applications
Volume: 1 Year: 2023
Author(s):
Doi: 10.2174/9789815179095123010005

Automation in Medicinal Chemistry

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 7 Year: 2004 Page: 671-686
Author(s): John C. Reader

A Parallel Synthesis Demonstration Library of Tri-Substituted Indazoles Containing New Antimutagenic / Antioxidant Hits Related to Benzydamine

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 5 Year: 2003 Page: 471-480
Author(s): Sanjay Menon, Hemin Vaidya, Segaran Pillai, Ramdas Vidya, Lester A. Mitscher

Review Article

Ligand- and Structure-Based Drug Design and Optimization using KNIME

Journal: Current Medicinal Chemistry
Volume: 27 Issue: 38 Year: 2020 Page: 6458-6479
Author(s): Michael P. Mazanetz,Charlotte H.F. Goode,Ewa I. Chudyk

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