Search Result "HERG inhibitors"


Ligand Structural Aspects of hERG Channel Blockade

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1113-1127
Author(s): Alex M. Aronov

In Silico hERG Modeling: Challenges and Progress

Journal: Current Computer-Aided Drug Design
Volume: 5 Issue: 2 Year: 2009 Page: 106-121
Author(s): David J. Diller

Tuning hERG Out: Antitarget QSAR Models for Drug Development

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 11 Year: 2014 Page: 1399-1415
Author(s): Rodolpho C. Braga,Vinicius M. Alves,Meryck F.B. Silva,Eugene Muratov,Denis Fourches,Alexander Tropsha,Carolina H. Andrade

The hERG Channel and Risk of Drug-Acquired Cardiac Arrhythmia: An Overview

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1102-1112
Author(s): Armando A. Lagrutta, Elena S. Trepakova, Joseph J. Salata

Overcoming hERG Affinity in the Discovery of Maraviroc; A CCR5 Antagonist for the Treatment of HIV

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1140-1151
Author(s): David A. Price, Duncan Armour, Marcel de Groot, Derek Leishman, Carolyn Napier, Manos Perros, Blanda L. Stammen, Anthony Wood

Strategies for the Design of Selective Protein Kinase Inhibitors

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1291-1297
Author(s): Masaaki Sawa

Research Article

Prediction and Experimental Evaluation of the hERG Blocking Potentialof Drugs Showing Clinical Signs of Cardiotoxicity

Journal: Letters in Drug Design & Discovery
Volume: 20 Issue: 11 Year: 2023 Page: 1757-1767
Author(s):

QSAR and Pharmacophore Analysis of a Series of Piperidinyl Urea Derivatives as hERG Blockers and H3 Antagonists

Journal: Current Drug Discovery Technologies
Volume: 10 Issue: 1 Year: 2013 Page: 47-58
Author(s): N. S. Hari Narayana Moorthy, Maria J. Ramos, Pedro A. Fernandes

In Silico Predictions of hERG Channel Blockers in Drug Discovery: From Ligand-Based and Target-Based Approaches to Systems Chemical Biology

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 5 Year: 2011 Page: 375-387
Author(s): Olivier Taboureau, Flemming Steen Jorgensen

Review Article

Computational Models for Understanding of Structure, Function and Pharmacology of the Cardiac Potassium Channel Kv11.1 (hERG)

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 23 Year: 2017 Page: 2681-2702
Author(s): Soren Wacker,Sergei Yu. Noskov,Laura L. Perissinotti

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