Search Result "FTI"


Farnesyltransferase Inhibitors: A Detailed Chemical View on an Elusive Biological Problem

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2008 Page: 1478-1492
Author(s): Sergio F. Sousa, Pedro A. Fernandes, Maria Joao Ramos

Targeting the Process of Farynesylation for Therapy of Hematologic Malignancies

Journal: Current Molecular Medicine
Volume: 5 Issue: 7 Year: 2005 Page: 643-652
Author(s): Judith E. Karp, Jeffrey E. Lancet

Quantitative Structure-activity Relationships of Imidazole-containing Farnesyltransferase Inhibitors Using Different Chemometric Methods

Journal: Medicinal Chemistry
Volume: 9 Issue: 3 Year: 2013 Page: 434-448
Author(s): Ali Shayanfar,Saeed Ghasemi,Somaieh Soltani,Karim Asadpour-Zeynali,Robert J. Doerksen,Abolghasem Jouyban

Farnesyltransferase Inhibitors: A Comprehensive Review Based on Quantitative Structural Analysis

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 3 Year: 2013 Page: 4888-4923
Author(s): N. S.H.N. Moorthy, S. F. Sousa, M. J. Ramos, P. A. Fernandes

Farnesylated Proteins as Anticancer Drug Targets: From Laboratory to the Clinic

Journal: Current Medicinal Chemistry - Anti-Cancer Agents
Volume: 4 Issue: 2 Year: 2004 Page: 123-138
Author(s): Patrizia Russo, Maura Loprevite, Alfredo Cesario, Andrea Ardizzoni

Sch-66336 (Sarasar®) and Other Benzocycloheptapyridyl Farnesyl Protein Transferase Inhibitors: Discovery, Biology and Clinical Observations

Journal: Current Topics in Medicinal Chemistry
Volume: 3 Issue: 1 Year: 2003 Page: 1103-1114
Author(s): Arthur G. Taveras, Paul Kirschmeier, Charles M. Baum

Farnesyltransferase Inhibitor as Anticancer Agent

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 9 Issue: 6 Year: 2009 Page: 638-652
Author(s): Anuj G. Agrawal, Rakesh R. Somani

Isoprenylation of Intracellular Proteins as a New Target for the Therapy of Human Neoplasms: Preclinical and Clinical Implications

Journal: Current Drug Targets
Volume: 6 Issue: 3 Year: 2005 Page: 301-323
Author(s): M. Caraglia, A. Budillon, P. Tagliaferri, M. Marra, A. Abbruzzese, F. Caponigro

Non-Peptidic Prenyltransferase Inhibitors: Diverse Structural Classes and Surprising Anti-Cancer Mechanisms

Journal: Current Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2001 Page: 1437-1465
Author(s): Richard A. Gibbs, Todd J. Zahn, Judith S. Sebolt-Leopold

Increasing Complexity of Farnesyltransferase Inhibitors Activity: Role in Chromosome Instability

Journal: Current Cancer Drug Targets
Volume: 3 Issue: 2 Year: 2003 Page: 109-118
Author(s): Carla Falugi, Sonya Trombino, Pierluigi Granone, Stefano Margaritora, Patrizia Russo

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