Search Result "Elacridar"


A Simplified Protocol Employing Elacridar in Rodents: A Screening Model in Drug Discovery to Assess P-gp Mediated Efflux at the Blood Brain Barrier

Journal: Drug Metabolism Letters
Volume: 6 Issue: 2 Year: 2012 Page: 134-144
Author(s): Rajareddy Kallem,Chetan P. Kulkarni,Dakshay Patel,Megha Thakur,Michael Sinz,Sheelendra P. Singh,S. Shahe Mahammad,Sandhya Mandlekar

Substrates, Inhibitors and Activators of P-glycoprotein: Candidates for Radiolabeling and Imaging Perspectives

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1703-1714
Author(s): Nicola A. Colabufo, Francesco Berardi, Maria Grazia Perrone, Elena Capparelli, Mariangela Cantore, Carmela Inglese, Roberto Perrone

Review Article

Role of ATP-Binding Cassette Transporter Proteins in CNS Tumors: Resistance- Based Perspectives and Clinical Updates

Journal: Current Pharmaceutical Design
Volume: 26 Issue: 37 Year: 2020 Page: 4747-4763
Author(s): M. Asif,M. Usman,Shahid Ayub,Sahar Farhat,Zilli Huma,Jawad Ahmed,Mohammad A. Kamal,Deema Hussein,Aneela Javed,Ishaq Khan

Modulation and Absorption of Xenobiotics: The Synergistic Role of CYP450 and P-gp Activities in Cancer and Neurodegenerative Disorders

Journal: Current Drug Metabolism
Volume: 12 Issue: 8 Year: 2011 Page: 702-712
Author(s): Carmela Inglese, Maria Grazia Perrone, Francesco Berardi, Roberto Perrone, Nicola Antonio Colabufo

Review Article

Kinetic Models for Measuring P-glycoprotein Function at the Blood-Brain Barrier with Positron Emission Tomography

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 38 Year: 2016 Page: 5786-5792
Author(s): Mark Lubberink

Research Article

Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions

Journal: Drug Metabolism Letters
Volume: 12 Issue: 1 Year: 2018 Page: 3-13
Author(s): Susan Wong,Utkarsh Doshi,Peter Vuong,Ning Liu,Suzanne Tay,Hoa Le,Mika Kosaka,Jane R. Kenny,Albert P. Li,Zhengyin Yan

Current Frontiers

The Tetrahydroisoquinoline Scaffold in ABC Transporter Inhibitors that Act as Multidrug Resistance (MDR) Reversers

Journal: Current Topics in Medicinal Chemistry
Volume: 22 Issue: 31 Year: 2022 Page: 2535-2569
Author(s): Maria Novella Romanelli

Carbon-11 Labeled Tracers for In Vivo Imaging of P-Glycoprotein Function: Kinetics, Advantages and Disadvantages

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1820-1833
Author(s): Gert Luurtsema, Joost Verbeek, Mark Lubberink, Adriaan A. Lammertsma, Rudi Dierckx, Philip Elsinga, Albert D. Windhorst, Aren van Waarde

Review Article

Relevance of Breast Cancer Resistance Protein to Brain Distribution and Central Acting Drugs: A Pharmacokinetic Perspective

Journal: Current Drug Metabolism
Volume: 19 Issue: 1 Year: 2018 Page: 1021-1041
Author(s): Joana Goncalves,Joana Bicker,Gilberto Alves,Ana Fortuna,Amilcar Falcao

Imaging of P-glycoprotein Function and Expression to Elucidate Mechanisms of Pharmacoresistance in Epilepsy

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1785-1791
Author(s): Wolfgang Loscher, Oliver Langer

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