Search Result "DMPK screens"


The Influence of DMPK as an Integrated Partner in Modern Drug Discovery

Journal: Current Drug Metabolism
Volume: 3 Issue: 5 Year: 2002 Page: 527-550
Author(s): Robert J. Riley, Iain J. Martin, Anne E. Cooper

Utility of Mass Spectrometry for In-Vitro ADME Assays

Journal: Current Drug Metabolism
Volume: 7 Issue: 5 Year: 2006 Page: 467-477
Author(s): Inhou Chu, Amin A.Nomeir

Recent Advances in High Throughput Screening for ADME Properties

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 3 Year: 2008 Page: 258-264
Author(s): Timothy J. Carlson, Michael B. Fisher

Increasing Speed and Throughput When Using HPLC-MS/MS Systems forDrug Metabolism and Pharmacokinetic Screening

Journal: Current Drug Metabolism
Volume: 7 Issue: 5 Year: 2006 Page: 479-489
Author(s): Yunsheng Hsieh, Walter A. Korfmacher

The Role of Exploratory Drug Metabolism and Pharmacokinetics in New Drug Research: Case Study-Selection of a Thrombin Receptor Antagonist for Development

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 1 Year: 2009 Page: 2262-2269
Author(s): Yunsheng Hsieh, K.-C. Cheng, Yuguang Wang, Samuel Chackalamannil, Yan Xia, Walter A. Korfmacher, Ronald E. White

Advances in the Integration of Drug Metabolism into the Lead Optimization Paradigm

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 9 Issue: 6 Year: 2009 Page: 703-716
Author(s): Walter A. Korfmacher

Novel, Acidic CCR2 Receptor Antagonists: Lead Optimization

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 4 Year: 2007 Page: 263-271
Author(s): O. A. Dasse, J. L. Evans, H.-X. Zhai, D. Zou, J. T. Kintigh, F. Chan, K. Hamilton, E. Hill, J. B. Eckman, P. J. Higgins, A. Volosov, P. Collart, J.-M. Nicolas, R.K. Kondru, C.E. Schwartz

A Proposed Screening Paradigm for Discovery of Covalent Inhibitor Drugs

Journal: Drug Metabolism Letters
Volume: 8 Issue: 1 Year: 2014 Page: 19-30
Author(s): Mehran F. Moghaddam,Yang Tang,Zhihong O’Brien,Samantha J. Richardson,Maria Bacolod,Prasoon Chaturedi,Julius Apuy,Ashutosh Kulkarni

High Throughput Screening of Physicochemical Properties and In Vitro ADME Profiling in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 3 Year: 2009 Page: 315-329
Author(s): Hong Wan, Anders G. Holmen

Finding New Hits in Neglected Disease Projects: Target or Phenotypic Based Screening?

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1284-1291
Author(s): Ian H. Gilbert, Didier Leroy, Julie A. Frearson

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