Search Result "COX-1 inhibition"


Selective COX-1 Inhibition: A Therapeutic Target to be Reconsidered

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 3769-3805
Author(s): M. G. Perrone, A. Scilimati, L. Simone, P. Vitale

Clinical Implications of COX-1 and / or COX-2 Inhibition for the Distal Gastrointestinal Tract

Journal: Current Pharmaceutical Design
Volume: 9 Issue: 2 Year: 2003 Page: 2253-2266
Author(s): Angel Lanas, Julian Panes, Josep M. Pique

Update on SAR Studies Toward New COX-1 Selective Inhibitors

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 37 Year: 2015 Page: 4271-4292
Author(s): Paola Vitale,Antonio Scilimati,Maria Grazia Perrone

Research Article

Evaluation of the Effect of α-L-Guluronic Acid (G2013) on COX-1, COX-2 Activity and Gene Expression for Introducing this Drug as a Novel NSAID with Immunomodulatory Property

Journal: Recent Patents on Inflammation & Allergy Drug Discovery
Volume: 12 Issue: 2 Year: 2018 Page: 162-168
Author(s): Abbas Mirshafiey,Seyed S. Mortazavi-Jahromi,Mahsa Taeb,Salvatore Cuzzocrea,Emanuela Esposito

The Molecular Basis of COX-2 Versus COX-1 Selectivity of Lumiracoxib by Molecular Docking Studies

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 6 Year: 2007 Page: 422-425
Author(s): Celia M. Correa, Andre F. de Paula, Gilberto M.S. da Silva, Carlos M.R. SantAnna, Carlos A. M. Fraga, Eliezer J. Barreiro

Research Article

Design, Synthesis and Biological Evaluation of New 1,3-diphenyl-3- (phenylamino)propan-1-ones as Selective Cyclooxygenase (COX-2) Inhibitors

Journal: Medicinal Chemistry
Volume: 14 Issue: 7 Year: 2018 Page: 652-659
Author(s): Shabnam Farzaneh,Soraya Shahhosseini,Hadi Arefi,Bahram Daraei,Marjan Esfahanizadeh,Afshin Zarghi

The Role of COX-1 and COX-2 in Alzheimers Disease Pathology and the Therapeutic Potentials of Non-Steroidal Anti-Inflammatory Drugs

Journal: Current Drug Targets - CNS & Neurological Disorders
Volume: 4 Issue: 3 Year: 2005 Page: 307-315
Author(s): Jeroen J.M. Hoozemans, M. Kerry OBanion

Ester Prodrugs of Ketoprofen: Synthesis, In Vitro Stability, In Vivo Biological Evaluation and In Silico Comparative Docking Studies Against COX-1 and COX-2

Journal: Current Drug Discovery Technologies
Volume: 13 Issue: 1 Year: 2016 Page: 41-57
Author(s): Musa Ahmed,Faizul Azam,Abdul Gbaj,Abdulmottaleb E. Zetrini,Amna S. Abodlal,Abir Rghigh,Eman Elmahdi,Amel Hamza,Mabruk Salama,Salah M. Bensaber

Chebulagic Acid Synergizes the Cytotoxicity of Doxorubicin in Human Hepatocellular Carcinoma Through COX-2 Dependant Modulation of MDR-1

Journal: Medicinal Chemistry
Volume: 7 Issue: 5 Year: 2011 Page: 432-442
Author(s): Chandrani Achari, Gorla V. Reddy, T. C.M. Reddy, Pallu Reddanna

Structural and Electronic Factors Influencing the Selective Inhibition of COX-2

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 16 Issue: 7 Year: 2016 Page: 579-594
Author(s): Fatma Aksakal,Natali Shvets,Veronika Khairullina,Anatholy Dimoglo

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