Search Result "COX-1 enzyme"


Research Article

Evaluation of the Effect of α-L-Guluronic Acid (G2013) on COX-1, COX-2 Activity and Gene Expression for Introducing this Drug as a Novel NSAID with Immunomodulatory Property

Journal: Recent Patents on Inflammation & Allergy Drug Discovery
Volume: 12 Issue: 2 Year: 2018 Page: 162-168
Author(s): Abbas Mirshafiey,Seyed S. Mortazavi-Jahromi,Mahsa Taeb,Salvatore Cuzzocrea,Emanuela Esposito

Update on SAR Studies Toward New COX-1 Selective Inhibitors

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 37 Year: 2015 Page: 4271-4292
Author(s): Paola Vitale,Antonio Scilimati,Maria Grazia Perrone

Cyclooxygenase Enzymes: Regulation and Function

Journal: Current Pharmaceutical Design
Volume: 10 Issue: 6 Year: 2004 Page: 577-588
Author(s): F. A. Fitzpatrick

Selective COX-1 Inhibition: A Therapeutic Target to be Reconsidered

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 3769-3805
Author(s): M. G. Perrone, A. Scilimati, L. Simone, P. Vitale

The Molecular Basis of COX-2 Versus COX-1 Selectivity of Lumiracoxib by Molecular Docking Studies

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 6 Year: 2007 Page: 422-425
Author(s): Celia M. Correa, Andre F. de Paula, Gilberto M.S. da Silva, Carlos M.R. SantAnna, Carlos A. M. Fraga, Eliezer J. Barreiro

Clinical Implications of COX-1 and / or COX-2 Inhibition for the Distal Gastrointestinal Tract

Journal: Current Pharmaceutical Design
Volume: 9 Issue: 2 Year: 2003 Page: 2253-2266
Author(s): Angel Lanas, Julian Panes, Josep M. Pique

Ester Prodrugs of Ketoprofen: Synthesis, In Vitro Stability, In Vivo Biological Evaluation and In Silico Comparative Docking Studies Against COX-1 and COX-2

Journal: Current Drug Discovery Technologies
Volume: 13 Issue: 1 Year: 2016 Page: 41-57
Author(s): Musa Ahmed,Faizul Azam,Abdul Gbaj,Abdulmottaleb E. Zetrini,Amna S. Abodlal,Abir Rghigh,Eman Elmahdi,Amel Hamza,Mabruk Salama,Salah M. Bensaber

Research Article

Design, Synthesis and Biological Evaluation of New 1,3-diphenyl-3- (phenylamino)propan-1-ones as Selective Cyclooxygenase (COX-2) Inhibitors

Journal: Medicinal Chemistry
Volume: 14 Issue: 7 Year: 2018 Page: 652-659
Author(s): Shabnam Farzaneh,Soraya Shahhosseini,Hadi Arefi,Bahram Daraei,Marjan Esfahanizadeh,Afshin Zarghi

Non-Selective Inhibition of Cyclooxygenase Enzymes by Aminoacetylenic Isoindoline 1,3-Diones

Journal: Inflammation & Allergy - Drug Targets (Discontinued)
Volume: 11 Issue: 5 Year: 2012 Page: 369-374
Author(s): Nidal A. Qinna,Zuhair A. Muhi-eldeen,Mohammad Ghattas,Tawfiq M. Alhussainy,Jenan Al-Qaisi,Khalid Z. Matalka

Chebulagic Acid Synergizes the Cytotoxicity of Doxorubicin in Human Hepatocellular Carcinoma Through COX-2 Dependant Modulation of MDR-1

Journal: Medicinal Chemistry
Volume: 7 Issue: 5 Year: 2011 Page: 432-442
Author(s): Chandrani Achari, Gorla V. Reddy, T. C.M. Reddy, Pallu Reddanna

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