Search Result "CLint"
Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the “Advanced Dissolution, Absorption, Metabolism (ADAM)” Model
Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 716-729
Author(s): A. S. Darwich, S. Neuhoff, M. Jamei, A. Rostami-Hodjegan
Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model
Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas
The Impact of In Vitro Binding on In Vitro - In Vivo Extrapolations, Projections of Metabolic Clearance and Clinical Drug-Drug Interactions
Journal: Current Drug Metabolism
Volume: 7 Issue: 3 Year: 2006 Page: 251-264
Author(s): K. Grime, R. J. Riley
Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in DifferentCYP3A4 Genotype Recombinant Metabolic Enzyme Systems
Journal: Current Drug Metabolism
Volume: 25 Issue: 2 Year: 2024 Page: 174-177
Author(s):
In Vitro Screening of Metabolic Clearance Using Two Concentration Points
Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 233-240
Author(s): Eric T. Williams, Nadia Farah, Robert D. Pelletier, W. George Lai
Comparison of Metabolic Soft Spot Predictions of CYP3A4, CYP2C9 and CYP2D6 Substrates Using MetaSite and StarDrop
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 9 Year: 2011 Page: 811-823
Author(s): Young G. Shin, Hoa Le, Cyrus Khojasteh, Cornelis E.C.A. Hop
In Vitro Metabolic Profiling of Periplogenin in Rat Liver Microsomes and its Associated Enzyme-kinetic Evaluation
Journal: Current Pharmaceutical Analysis
Volume: 16 Issue: 5 Year: 2020 Page: 504-512
Author(s): Yingshu Feng,Jinyi Wan,Baoding Chen,Yuan Zhu,Caleb Kesse Firempong,Chunlai Feng,Teruko Imai,Ximing Xu,Jiangnan Yu
Scaling In Vivo Pharmacokinetics from In Vitro Metabolic Stability Data in Drug Discovery
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 159-169
Author(s): Wendy Klopf, Philip Worboys
Extrahepatic Metabolism may Complicate the IVIVC in Rats
Journal: Drug Metabolism Letters
Volume: 8 Issue: 1 Year: 2014 Page: 51-66
Author(s): Massimiliano Fonsi
The Use of In Vitro Methods to Predict In Vivo Pharmacokinetics and Drug Interactions
Journal: Current Drug Metabolism
Volume: 2 Issue: 3 Year: 2001 Page: 299-314
Author(s): K. A. Bachmann, R. Ghosh