Search Result "CFTR modulator"


Targeting CFTR: How to Treat Cystic Fibrosis by CFTR-Repairing Therapies

Journal: Current Drug Targets
Volume: 12 Issue: 5 Year: 2011 Page: 683-693
Author(s): Margarida D. Amaral

On the Discovery and Development of CFTR Chloride Channel Activators

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 4 Year: 2006 Page: 471-484
Author(s): Frederic Becq

SUMOylation Modulates CFTR Biogenesis: Is the Pathway Druggable?

Journal: Current Drug Targets
Volume: 16 Issue: 9 Year: 2015 Page: 965-975
Author(s): Annette Ahner,Raymond A. Frizzell

CFTR Chloride Channel Drug Discovery - Inhibitors as Antidiarrheals and Activators for Therapy of Cystic Fibrosis

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 1 Year: 2006 Page: 2235-2247
Author(s): A. S. Verkman, Gergely L. Lukacs, Luis J.V. Galietta

Pharmacological Correction of Cystic Fibrosis: Molecular Mechanisms at the Plasma Membrane to Augment Mutant CFTR Function

Journal: Current Drug Targets
Volume: 17 Issue: 11 Year: 2016 Page: 1275-1281
Author(s): Kavisha Arora,Anjaparavanda P. Naren

CFTR Regulation of Aquaporin-Mediated Water Transport: A Target in Male Fertility

Journal: Current Drug Targets
Volume: 16 Issue: 9 Year: 2015 Page: 993-1006
Author(s): Marco G. Alves,Rosália Sá,Tito T. Jesus,Mário Sousa,Pedro F. Oliveira

F508del-CFTR Rescue: A Matter of Cell Stress Response

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 1 Year: 2013 Page: 3476-3496
Author(s): Erika Nieddu, Benedetta Pollarolo, Luisa Merello, Silvia Schenone, Mauro Mazzei

Identification and Validation of Hits from High Throughput Screens for CFTR Modulators

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 5 Year: 2012 Page: 628-641
Author(s): Stan Pasyk, Steven Molinski, Wilson Yu, Paul D.W. Eckford, Christine E. Bear

The Use of Small Molecules to Correct Defects in CFTR Folding, Maturation, and Channel Activity

Journal: Current Chemical Biology
Volume: 3 Issue: 1 Year: 2009 Page: 100-111
Author(s): Meredith F.N. Rosser, Diane E. Grove, Douglas M. Cyr

Can Correcting the ΔF508-CFTR Proteostasis-Defect Rescue CF Lung Disease?

Journal: Current Molecular Medicine
Volume: 12 Issue: 7 Year: 2012 Page: 860-871
Author(s): C. W. Valle,N. Vij

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