Search Result "B-RAF mutation"


Review Article

Helix-Coil Transition Signatures B-Raf V600E Mutation and Virtual Screening for Inhibitors Directed Against Mutant B-Raf

Journal: Current Drug Metabolism
Volume: 18 Issue: 6 Year: 2017 Page: 527-534
Author(s): Srinivas Bandaru,Tharaparambil Gangadharan Sumithnath,Saphy Sharda,Sanskruti Lakhotia,Anudeep Sharma,Amrita Jain,Tajamul Hussain,Anuraj Nayarisseri,Sanjeev Kumar Singh

Recent Advances in the Research and Development of B-Raf Inhibitors

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2010 Page: 1618-1634
Author(s): Hui-Fang Li, Yadong Chen, Sha-Sha Rao, Xiu-Mei Chen, Hai-Chun Liu, Ji-Hong Qin, Wei-Fang Tang, Yue-Wang, Xiang Zhou, Tao Lu

Review Article

Mutant B-Raf Kinase Inhibitors as Anticancer Agents

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 16 Issue: 12 Year: 2016 Page: 1558-1575
Author(s): Vivek Asati,Sanjay K. Bharti,Debarshi K. Mahapatra

Review Article

A Progressive Review of V600E-B-RAF-Dependent Melanoma and Drugs Inhibiting It

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 17 Issue: 4 Year: 2017 Page: 351-365
Author(s): Mohammad Ashrafuddin Khan,Mohammed I. El-Gamal,Chang-Hyun Oh

Pharmacophore and Binding Analysis of Known and Novel B-RAF Kinase Inhibitors

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 17 Year: 2014 Page: 1938-1955
Author(s): F. Baska,I. Szabadkai,A. Sipos,N. Breza,C. Szantai-Kis,L. Kekesi,R. Garamvolgyi,Z. Nemes,F. Baska,L. Neumann,R. Torka,A. Ullrich,G. Keri,L. Orfi

Research Article

A Fluoro Derivative of Embelin, as Potent B-RAF Inhibitor in Melanoma

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 15 Year: 2021 Page: 2066-2074
Author(s): Arunkumar Babu,Shiny P. Laila,Annette Fernandez

Insight into the Binding of DFG-out Allosteric Inhibitors to B-Raf Kinase Using Molecular Dynamics and Free Energy Calculations

Journal: Current Computer-Aided Drug Design
Volume: 11 Issue: 2 Year: 2015 Page: 124-136
Author(s): Luis Coronel,Jose M. Granadino-Roldán,Marta Pinto,Maria S. Tomas,Maria D. Pujol,Jaime Rubio-Martinez

Research Article

Design, Synthesis and Antiproliferative Evaluation of Novel 1,2,4-Triazole/Schiff Base Hybrids with EGFR and B-RAF Inhibitory Activities

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 19 Issue: 5 Year: 2019 Page: 697-706
Author(s): Hany A.M. El-Sherief,Bahaa G.M. Youssif,Ahmed H. Abdelazeem,Mohamed Abdel-Aziz,Hamdy M. Abdel-Rahman

General Research Article

In Silico Design of New B-Raf Kinase Type-II Inhibitors Through Combined Molecular Modeling Studies

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 5 Year: 2019 Page: 570-583
Author(s): Weineng Zhou,Shuai Lu,Yanmin Zhang,Lingfeng Yin,Lu Zhu,Junnan Zhao,Tao Lu,Yadong Chen,Haichun Liu

Recent Developments in Anti-Cancer Agents Targeting the Ras/Raf/ MEK/ERK Pathway

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 4 Issue: 1 Year: 2009 Page: 28-35
Author(s): Kwong-Kwok Wong

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