Search Result "Acetyl-lysine (KAc) binding pocket"


Small-Molecule BET Inhibitors in Clinical and Preclinical Development and Their Therapeutic Potential

Journal: Current Topics in Medicinal Chemistry
Volume: 15 Issue: 8 Year: 2015 Page: 776-794
Author(s): Lei Yu,Zhen Wang,Zhang Zhang,Xiaomei Ren,Xiaoyun Lu,Ke Ding

Review Article

An Overview on Small Molecule Inhibitors of BRD4

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 16 Issue: 17 Year: 2016 Page: 1403-1414
Author(s): Wenhai Huang,Xiaoliang Zheng,Yewei Yang,Xiaoju Wang,Zhengrong Shen

Review Article

Recent Advances in the Development of CBP/p300 Bromodomain Inhibitors

Journal: Current Medicinal Chemistry
Volume: 27 Issue: 33 Year: 2020 Page: 5583-5598
Author(s): Ying Xiong,Mingming Zhang,Yingxia Li

Research Article

Charting the Bromodomain BRD4: Towards the Identification of Novel Inhibitors with Molecular Similarity and Receptor Mapping

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 9 Year: 2018 Page: 1002-1011
Author(s): Fernando D. Prieto-Martinez,Jose L. Medina-Franco

Identification of New Inhibitors for Human SIRT1: An in-silico Approach

Journal: Medicinal Chemistry
Volume: 12 Issue: 4 Year: 2016 Page: 347-361
Author(s): Balasundaram Padmanabhan,Manjula Ramu,Shruti Mathur,Sruthi Unni,Saravanamuthu Thiyagarajan

Review Article

Dual-target Inhibitors Based on BRD4: Novel Therapeutic Approaches for Cancer

Journal: Current Medicinal Chemistry
Volume: 28 Issue: 9 Year: 2021 Page: 1775-1795
Author(s): Sitao Zhang,Yanzhao Chen,Chengsen Tian,Yujing He,Zeru Tian,Yichao Wan,Tingting Liu

Review Article

Protein/ Hormone Based Nanoparticles as Carriers for Drugs Targeting Protein-Protein Interactions

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 6 Year: 2019 Page: 444-456
Author(s): Ebtesam Al-Suhaimi,Vijaya Ravinayagam,B. Rabindran Jermy,Tarhini Mohamad,Abdelhamid Elaissari

E2F1-Mediated Apoptosis as a Target of Cancer Therapy

Journal: Current Molecular Pharmacology
Volume: 2 Issue: 2 Year: 2009 Page: 149-160
Author(s): Zhenlong Wu, Qiang Yu

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