Search Result "AL. DFG-out"


Insight into the Binding of DFG-out Allosteric Inhibitors to B-Raf Kinase Using Molecular Dynamics and Free Energy Calculations

Journal: Current Computer-Aided Drug Design
Volume: 11 Issue: 2 Year: 2015 Page: 124-136
Author(s): Luis Coronel,Jose M. Granadino-Roldán,Marta Pinto,Maria S. Tomas,Maria D. Pujol,Jaime Rubio-Martinez

Biochemical Markers in CSF of ALS Patients

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2008 Page: 1788-1801
Author(s): Sigurd D. Sussmuth, Johannes Brettschneider, Albert C. Ludolph, Hayrettin Tumani

Design, Synthesis and Antitumor Activities of Bis-arylureas and Bis-arylamides Based on1H-benzo[d]imidazole Moiety as Novel BRafV600E/VEGFR2 Dual inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 11 Issue: 9 Year: 2014 Page: 1079-1089
Author(s): Weimin Yang,Yadong Chen,Yanmin Zhang,Sanzhi Tang,Hongli Chen,Weifang Tang,Tao Lu

Discovery of Small Molecule c-Met Inhibitors: Evolution and Profiles of Clinical Candidates

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 7-27
Author(s): Ted L. Underiner, Torsten Herbertz, Sheila J. Miknyoczki

In silico Studies Toward the Discovery of Novel Type-II Inhibitors of TrkA: Pharmacophore-based 3D-QSAR Modeling, Database Screening and Molecular Docking

Journal: Letters in Drug Design & Discovery
Volume: 13 Issue: 6 Year: 2016 Page: 526-538
Author(s): Yahui Tian,Lu Zhou,Xiaoli Li,Suwen Zhou,Rong Yong,Liangliang Zhong

Successful Structure-Based Design of Recent p38 MAP Kinase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 7 Year: 2009 Page: 655-676
Author(s): Solveigh C. Karcher, Stefan A. Laufer

Diaryl Urea: A Privileged Structure in Anticancer Agents

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 15 Year: 2016 Page: 1528-1548
Author(s): Laura Garuti,Marinella Roberti,Giovanni Bottegoni,Mariarosaria Ferraro

Recent Developments in the Third Generation Inhibitors of Bcr-Abl for Overriding T315I Mutation

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2146-2157
Author(s): X. Y. Lu, Q. Cai, K. Ding

Screening for Inhibitors of Tau Protein Aggregation into Alzheimer Paired Helical Filaments: A Ligand Based Approach Results in Successful Scaffold Hopping

Journal: Current Alzheimer Research
Volume: 4 Issue: 3 Year: 2007 Page: 315-323
Author(s): Gregor Larbig, Marcus Pickhardt, David G. Lloyd, Boris Schmidt, Eckhard Mandelkow

Quantitative Structure-Activity Relationship Analysis of the Cation Permeability of the P2X2 Channel

Journal: Medicinal Chemistry
Volume: 1 Issue: 2 Year: 2005 Page: 109-115
Author(s): Peter P. Mager, Anje Weber, Peter Illes

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