Search Result "2(1H)-pyrazinone scaffold"


Review Article

A Review of the Pharmacological Properties of 3,4-dihydro-2(1H)- quinolinones

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 828-836
Author(s): Letitia Meiring,Jacobus P. Petzer,Anel Petzer

Research Article

2-((1H-1,2,3-triazol-1-yl)methyl)-3-phenylquinazolin-4(3H)-ones: Design, Synthesis and Evaluation as Anti-cancer Agents

Journal: Current Bioactive Compounds
Volume: 14 Issue: 3 Year: 2018 Page: 254-263
Author(s): Kamala K. Vasu,Hemantkumar D. Ingawale,Sneha R. Sagar,Jayesh A. Sharma,Dhaivat H. Pandya,Milee Agarwal

Research Article

Highly Enantioselective Synthesis of the 6-isopropyl-3,4-dihydropyrimidin-2-(1H)-thiones via Asymmetric Catalytic Biginelli Reactions

Journal: Current Organic Chemistry
Volume: 20 Issue: 27 Year: 2016 Page: 2917-2925
Author(s): Zhijun Hang,Guoyong Dai,Han Yu,Sheng Han

General Research Article

Comparison of Conventional and Microwave Synthesis of Phenyl-1H-pyrazoles and Phenyl-1H-pyrazoles-4-carboxylic Acid Derivatives

Journal: Current Organic Synthesis
Volume: 18 Issue: 8 Year: 2021 Page: 844-853
Author(s): Antônio S. Machado,Flávio S. de Carvalho,Rayssa B.P. Mouraa,Lorrayne S. Chaves,Luciano M. Lião,Germãn Sanz,Boniek G. Vaz,Marcella F. Rodrigues,Wanderson Romão,Ricardo Menegatti,Gloria N.S. Silva

Solid-Phase Synthesis of Structurally Diverse Scaffolded Peptides for the Mimicry of Discontinuous Protein Binding Sites

Journal: Protein & Peptide Letters
Volume: 10 Issue: 6 Year: 2003 Page: 531-539
Author(s): Raimo Franke, Christian Doll, Victor Wray, Jutta Eichler

4(1H)-Pyridone and 4(1H)-Quinolone Derivatives as Antimalarials with Erythrocytic, Exoerythrocytic, and Transmission Blocking Activities

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 14 Year: 2014 Page: 1693-1705
Author(s): Andrii Monastyrskyi,Dennis E. Kyle,Roman Manetsch

One-pot, Solvent-free Cascade Michael-reductive Cyclization Reaction for the Synthesis of Ethyl 3,5-disubstituted-1H-pyrrole-2-carboxylates Under Microwave Irradiation

Journal: Current Microwave Chemistry
Volume: 1 Issue: 2 Year: 2014 Page: 110-118
Author(s): Rajni Khajuria,Kamal K. Kapoor

Research Article

Molecular Design and Synthesis of New 3,4-Dihydropyrimidin-2(1H)-Ones as Potential Anticancer Agents with VEGFR-2 Inhibiting Activity

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 19 Issue: 3 Year: 2019 Page: 310-322
Author(s): Amany S. Mostafa,Waleed A. Bayoumi,Mohamed El-Mesery,Abdelaziz Elgaml

Research Article

The Oxime Derivatives of 1-R-1H-Naphtho[2,3-d][1,2,3]triazole-4,9-dione 2-oxides: Synthesis and Properties

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 17 Issue: 13 Year: 2017 Page: 1814-1823
Author(s): Leonid M. Gornostaev,Vladimir B. Tsvetkov,Alina A. Markova,Tatyana I. Lavrikova,Yulia G. Khalyavina,Anastasia S. Kuznetsova,Dmitry N. Kaluzhny,Alexei V. Shunayev,Maria V. Tsvetkova,Valeria A. Glazunova,Vladimir V. Chernyshev,Alexander A. Shtil

Research Article

Design, Synthesis and in silico Studies of New 5-substituted-2-(2-(5-aryl- 1H-1, 2, 4-triazole-3-ylthio) acetyl) Hydrazine Carbothioamide/ Carboxamides for Anticonvulsant Activity

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 10 Year: 2017 Page: 1155-1163
Author(s): Radhika Chelamalla,Ajitha Makula,Sarangapani Manda

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