Search Result "1-aminobenzotriazole"
The Use of 1-Aminobenzotriazole in Differentiating the Role of CYPMediated First Pass Metabolism and Absorption in Limiting Drug Oral Bioavailability: A Case Study
Journal: Drug Metabolism Letters
Volume: 2 Issue: 2 Year: 2008 Page: 120-124
Author(s): Ayman F. El-Kattan, Julie Poe, Lisa Buchholz, Hayden V. Thomas, Joanne Brodfuehrer, Alan Clark
Induction of CYP2B6 and CYP3A4 Expression by 1-Aminobenzotriazole (ABT) in Human Hepatocytes
Journal: Drug Metabolism Letters
Volume: 4 Issue: 3 Year: 2010 Page: 129-133
Author(s): Kyunghee Yang, Kwi Hye Koh, Hyunyoung Jeong
Higher Throughput Human Hepatocyte Assays for the Evaluation of Time-Dependent Inhibition of CYP3A4
Journal: Drug Metabolism Letters
Volume: 5 Issue: 3 Year: 2011 Page: 183-191
Author(s): Albert P. Li, Utkarsh Doshi
Oxidative Bioactivation and Toxicity of Leflunomide in Immortalized Human Hepatocytes and Kinetics of the Non-Enzymatic to Its Major etabolitie, A77 1726
Journal: Drug Metabolism Letters
Volume: 2 Issue: 3 Year: 2008 Page: 153-157
Author(s): Quee Ming Seah, Lee-Sun New, Eric C.Y. Chan, Urs A. Boeslsterli
Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat
Journal: Drug Metabolism Letters
Volume: 10 Issue: 2 Year: 2016 Page: 91-100
Author(s): Peter W. Fan, Jacob Z. Chen, M. Allan Jaochico, Hank La, Ning Liu, Teresa Mulder, Robert T. Cass, Matthew Durk, Kirsten Messick, Nicole Valle, Shannon Liu, Wendy Lee, James J. Crawford, Joachim Rudolf, Lesley J. Murray, S. Cyrus Khojasteh, Matthew Wright
The Effects of Drug Metabolizing Enzyme Inhibitors on Hepatic Efflux and Uptake Transporters
Journal: Drug Metabolism Letters
Volume: 11 Issue: 2 Year: 2017 Page: 111-118
Author(s): Jonathan Cheong,Jason S. Halladay,Emile Plise,Jasleen K. Sodhi,Laurent Salphati
Methodologies for Investigating Drug Metabolism at the Early Drug Discovery Stage: Prediction of Hepatic Drug Clearance and P450 Contribution
Journal: Current Drug Metabolism
Volume: 11 Issue: 8 Year: 2010 Page: 678-685
Author(s): Chie Emoto, Norie Murayama, Amin Rostami-Hodjegan, Hiroshi Yamazaki
Metabolic Activation of Retrorsine may Disrupt Bile Acid Homeostasis in Mice through the Nrf2 Pathway
Journal: Current Drug Metabolism
Volume: 22 Issue: 11 Year: 2021 Page: 870-881
Author(s): Xiaoyan Pang,Chongzhuang Tang,Peng Cao,Lei Zhou,Xiaoyan Chen
Reaction Phenotyping in Drug Discovery: Moving Forward with Confidence?
Journal: Current Drug Metabolism
Volume: 4 Issue: 6 Year: 2003 Page: 527-534
Author(s): J. Andrew Williams, Susan I. Hurst, Jonathan Bauman, Barry C. Jones, Ruth Hyland, John P. Gibbs, R. Scott Obach, Simon E. Ball
Triazoloquinolines I: Synthetic Methods and Pharmacological Properties of [1,2,3]triazoloquinoline Derivatives
Journal: Current Organic Chemistry
Volume: 25 Issue: 8 Year: 2021 Page: 876-893
Author(s): Rizk E. Khidre,Ibrahim M.A. Radini,Tahah A. Ameen,Ahmed A.M. Abdelgawad