Search Result "voltage-gated sodiumchannels"


Voltage Gated ion Channels: Targets for Anticonvulsant Drugs

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2005 Page: 15-30
Author(s): Adam C. Errington, Thomas Stohr, George Lees

Mechanism of Local Anesthetic Drug Action on Voltage-Gated Sodium Channels

Journal: Current Pharmaceutical Design
Volume: 11 Issue: 2 Year: 2005 Page: 2671-2686
Author(s): H. A. Fozzard, P. J. Lee, G. M. Lipkind

Blockers of Voltage-Gated Sodium Channels for the Treatment of Central Nervous System Diseases

Journal: Recent Patents on CNS Drug Discovery (Discontinued)
Volume: 2 Issue: 1 Year: 2007 Page: 57-78
Author(s): Istvan Tarnawa, Hedvig Bolcskei, Pal Kocsis

Review Article

Understanding Genotypes and Phenotypes of the Mutations in Voltage- Gated Sodium Channel α Subunits in Epilepsy

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 18 Issue: 4 Year: 2019 Page: 266-272
Author(s): Yijun Feng,Shuzhang Zhang,Zhiping Zhang,Jingkang Guo,Zhiyong Tan,Yudan Zhu,Jie Tao,Yong-Hua Ji

Voltage-Gated Sodium Channel Blockers; Target Validation and Therapeutic Potential

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 6 Year: 2005 Page: 529-537
Author(s): John N. Wood, James Boorman

Ion Channels as Important Targets for Antiepileptic Drug Design

Journal: Current Drug Targets
Volume: 5 Issue: 7 Year: 2004 Page: 589-602
Author(s): P. Yogeeswari, J. Vaigunda Ragavendran, R. Thirumurugan, A. Saxena, D. Sriram

An Improved Synthesis of m-Hydroxymexiletine, a Potent Mexiletine Metabolite

Journal: Drug Metabolism Letters
Volume: 6 Issue: 2 Year: 2012 Page: 124-128
Author(s): Alessia Catalano,Alessia Carocci,Giovanni Lentini,Ivana Defrenza,Maria Maddalena Cavalluzzi,Carlo Franchini

Cardiotoxic and Antiarrhythmic Tertiary Amine Local Anesthetics: Sodium Channel Affinity vs. Sodium Channel Gating

Journal: Current Vascular Pharmacology
Volume: 1 Issue: 3 Year: 2003 Page: 239-242
Author(s): Sterling N. Wright

Activity of Drugs and Components of Natural Origin in the Severe Myoclonic Epilepsy of Infancy (Dravet Syndrome)

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 15 Issue: 2 Year: 2015 Page: 95-98
Author(s): Agostino Berio,Attilia Piazzi

Review Article

Computational and Synthetic Target-based Approaches to the Discovery of Novel Anticonvulsant Compounds

Journal: Current Medicinal Chemistry
Volume: 28 Issue: 33 Year: 2021 Page: 6866-6894
Author(s): Melisa Edith Gantner,Manuel Augusto Llanos,Federico Mariano Garofalo,María Luisa Villalba,Luciana Gavernet

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