Search Result "time-dependent CYP inhibitor"


Higher Throughput Human Hepatocyte Assays for the Evaluation of Time-Dependent Inhibition of CYP3A4

Journal: Drug Metabolism Letters
Volume: 5 Issue: 3 Year: 2011 Page: 183-191
Author(s): Albert P. Li, Utkarsh Doshi

CYP Inhibition-Mediated Drug-Drug Interactions

Journal: Current Enzyme Inhibition
Volume: 6 Issue: 3 Year: 2010 Page: 130-145
Author(s): Karoly Tihanyi, Monika L. Bakk, Eva Hellinger, Monika Vastag

In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities

Journal: Drug Metabolism Letters
Volume: 9 Issue: 1 Year: 2015 Page: 48-62
Author(s): Charles Awortwe,Vamshi K. Manda,Cristina Avonto,Shabana I. Khan,Ikhlas A. Khan,Larry A. Walker,Patrick J. Bouic,Bernd Rosenkranz

Evaluation of Time-Dependent Cytochrome P450 Inhibition in a High-Throughput, Automated Assay: Introducing a Novel Area Under the Curve Shift Approach

Journal: Drug Metabolism Letters
Volume: 6 Issue: 1 Year: 2012 Page: 43-53
Author(s): Sophie Mukadam, Suzanne Tay, Daniel Tran, Leslie Wang, Erlie M. Delarosa, S. Cyrus Khojasteh, Jason S. Halladay, Jane R. Kenny

Enzyme Kinetics for Clinically Relevant CYP Inhibition

Journal: Current Drug Metabolism
Volume: 6 Issue: 3 Year: 2005 Page: 241-257
Author(s): Zhi-Yi Zhang, Y. Nancy Wong

Role of Microtubules Network in CYP Genes Expression

Journal: Current Drug Metabolism
Volume: 6 Issue: 6 Year: 2005 Page: 545-552
Author(s): Z. Dvorak, J. Ulrichova, M. Modriansky

Modulation of Cytochrome-P450 Inhibition (CYP) in Drug Discovery: A Medicinal Chemistry Perspective

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 21 Year: 2012 Page: 3605-3621
Author(s): Sanjay Kumar,Rajiv Sharma,Abhijit Roychowdhury

Inhibition of Major Drug Metabolizing CYPs by Common Herbal Medicines used by HIV/AIDS Patients in Africa– Implications for Herb- Drug Interactions

Journal: Drug Metabolism Letters
Volume: 7 Issue: 2 Year: 2013 Page: 83-95
Author(s): Charles Awortwe,Patrick J. Bouic,Collen M. Masimirembwa,Bernd Rosenkranz

Small Molecule Inhibitors of Peptidylprolyl cis/trans Isomerase

Journal: Current Enzyme Inhibition
Volume: 6 Issue: 1 Year: 2010 Page: 46-53
Author(s): Tadashi Mori, Takafumi Uchida

Research Article

In vitro Measurement and In vivo Prediction of Time-Dependent Inhibitory Effects of Three Tyrosine Kinase Inhibitors on CYP3A Activity

Journal: Current Drug Metabolism
Volume: 22 Issue: 10 Year: 2021 Page: 802-810
Author(s): Liyan Wang,Tingting Zhao,Yunxiang Wang,Banglian Hu,Jianfei Tao,Jinshan Ke,Tingfei Wei,Guangbo Ge,Qiang Meng,Changyuan Wang,Qi Liu,Huijun Sun,Jingjing Wu,Yanwei Chen

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