Search Result "systemic plasma clearance"


Prediction of Human Hepatic Clearance Using an In Vitro Plated Hepatocyte Clearance Model

Journal: Drug Metabolism Letters
Volume: 3 Issue: 4 Year: 2009 Page: 296-307
Author(s): Piyun Chao, Jeffrey Barminko, Eric Novik, Yi Han, Timothy Maguire, K.-C. Cheng

Review Article

Optimization of Protein and Peptide Drugs Based on the Mechanisms of Kidney Clearance

Journal: Protein & Peptide Letters
Volume: 25 Issue: 6 Year: 2018 Page: 514-521
Author(s): Huizi Wu,Jiaguo Huang

Application of Organ Clearance to Estimation of the In Vivo Hepatic Extraction Ratio

Journal: Current Clinical Pharmacology
Volume: 11 Issue: 1 Year: 2016 Page: 47-52
Author(s): Reza Mehvar

Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas

Predicting Clearance in Humans from In Vitro Data

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach

P-Glycoprotein, but not Multidrug Resistance Protein 4, Plays a Role in the Systemic Clearance of Irinotecan and SN-38 in Mice

Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 195-201
Author(s): Michael Tagen, Yanli Zhuang, Fan Zhang, K. Elaine Harstead, Jun Shen, Paula Schaiquevich, Charles H. Fraga, John C. Panetta, Christopher M. Waters, Clinton F. Stewart

Research Article

The Role of Aldehyde Oxidase in the Metabolic Clearance of Substituted Benzothiazoles

Journal: Drug Metabolism Letters
Volume: 14 Issue: 2 Year: 2021 Page: 126-136
Author(s): Yohannes Teffera,Jingzhou Liu,Paul Krolikowski,Zhiyang Zhao

Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 450-466
Author(s): Xingrong Liu, Cuiping Chen, Cornelis E.C.A. Hop

Research Article

Melatonin Treatment Enhances Aβ Lymphatic Clearance in a Transgenic Mouse Model of Amyloidosis

Journal: Current Alzheimer Research
Volume: 15 Issue: 7 Year: 2018 Page: 637-642
Author(s): M.A. Pappolla,E. Matsubara,R. Vidal,J. Pacheco-Quinto,B. Poeggeler,M. Zagorski,K. Sambamurti

Apoptotic Cell Clearance and Autoimmune Disorder

Journal: Current Medicinal Chemistry
Volume: 14 Issue: 2 Year: 2007 Page: 2892-2897
Author(s): Masato Tanaka, Yasunobu Miyake

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