Search Result "small-molecule PERK inhibitors."


Research Article

Use of Small-molecule Inhibitory Compound of PERK-dependent Signaling Pathway as a Promising Target-based Therapy for Colorectal Cancer

Journal: Current Cancer Drug Targets
Volume: 20 Issue: 3 Year: 2020 Page: 223-238
Author(s): Wioletta Rozpędek,Dariusz Pytel,Adam Wawrzynkiewicz,Natalia Siwecka,Adam Dziki,Łukasz Dziki,J. Alan Diehl,Ireneusz Majsterek

Review Article

Molecular Basis of Human Diseases and Targeted Therapy Based on Small-Molecule Inhibitors of ER Stress-Induced Signaling Pathways

Journal: Current Molecular Medicine
Volume: 17 Issue: 2 Year: 2017 Page: 118-132
Author(s): W. Rozpedek,A. Nowak,D. Pytel,J. Alan Diehl,I. Majsterek

Benzofuran Small Molecules as Potential Inhibitors of Human Protein Kinases. A Review

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 7 Year: 2016 Page: 879-894
Author(s): Halina Kwiecień,Agata Goszczyńska,Paulina Rokosz

Research Article

Inhibition of the PERK-Dependent Unfolded Protein Response Signaling Pathway Involved in the Pathogenesis of Alzheimer’s Disease

Journal: Current Alzheimer Research
Volume: 16 Issue: 3 Year: 2019 Page: 209-218
Author(s): Wioletta Rozpędek,Dariusz Pytel,Tomasz Popławski,Anna Walczak,Kinga Gradzik,Adam Wawrzynkiewicz,Radosław Wojtczak,Bartosz Mucha,John Alan Diehl,Ireneusz Majsterek

Unfolded Protein Response and PERK Kinase as a New Therapeutic Target in the Pathogenesis of Alzheimer’s Disease

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 27 Year: 2015 Page: 3169-3184
Author(s): Wioletta Rozpedek,Lukasz Markiewicz,J. Alan Diehl,Dariusz Pytel,Ireneusz Majsterek

Review Article

Breaking the DNA Damage Response via Serine/Threonine Kinase Inhibitors to Improve Cancer Treatment

Journal: Current Medicinal Chemistry
Volume: 26 Issue: 8 Year: 2019 Page: 1425-1445
Author(s): Wioletta Rozpędek,Dariusz Pytel,Alicja Nowak-Zduńczyk,Dawid Lewko,Radosław Wojtczak,J. Alan Diehl,Ireneusz Majsterek

Review Article

Small Molecule Drugs and Targeted Therapy for Melanoma: Current Strategies and Future Directions

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 21 Year: 2017 Page: 2312-2344
Author(s): Carmen Cerchia,Antonio Lavecchia

Small Molecules in Cancer Therapy: Cytotoxics and Molecularly Targeted Agents

Journal: Current Signal Transduction Therapy
Volume: 6 Issue: 1 Year: 2011 Page: 2-19
Author(s): Anna Blazovics

Review Article

Neuroregeneration in Parkinson’s Disease: From Proteins to Small Molecules

Journal: Current Neuropharmacology
Volume: 17 Issue: 3 Year: 2019 Page: 268-287
Author(s): Yulia A. Sidorova,Konstantin P. Volcho,Nariman F. Salakhutdinov

UCSF Small Molecule Discovery Center: Innovation, Collaboration and Chemical Biology in the Bay Area

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 4 Year: 2014 Page: 333-342
Author(s): Michelle R. Arkin,Kenny K.H. Ang,Steven Chen,Julia Davies,Connie Merron,Yinyan Tang,Christopher G.M. Wilson,Adam R. Renslo

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