Search Result "reactive metabolite screening"


A New Quaternary Ammonium Cysteine Analogue as a Trapping Reagent for Reactive Metabolites Screening

Journal: Drug Metabolism Letters
Volume: 8 Issue: 1 Year: 2014 Page: 36-42
Author(s): Natalia Penner,Xiaojing Liu,Chandra Prakash

Are Chemically Reactive Metabolites Responsible for Adverse Reactions to Drugs?

Journal: Current Drug Metabolism
Volume: 3 Issue: 4 Year: 2002 Page: 351-366
Author(s): D. P. Williams, N. R. Kitteringham, D. J. Naisbitt, M. Pirmohamed, D. A. Smith, B. K. Park

On Mechanisms of Reactive Metabolite Formation from Drugs

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 13 Issue: 5 Year: 2013 Page: 720-729
Author(s): Alf Claesson, Ola Spjuth

In Vitro Screening Techniques for Reactive Metabolites for Minimizing Bioactivation Potential in Drug Discovery

Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 952-964
Author(s): Chandra Prakash, Raman Sharma, Michelle Gleave, Angus Nedderman

Review Article

Reactive Metabolites: Generation and Estimation with Electrochemistry Based Analytical Strategy as an Emerging Screening Tool

Journal: Current Analytical Chemistry
Volume: 16 Issue: 7 Year: 2020 Page: 811-825
Author(s): Maria Bandookwala,Kavya Sri Nemani,Bappaditya Chatterjee,Pinaki Sengupta

Gauging Reactive Metabolites in Drug-Induced Toxicity

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 4 Year: 2015 Page: 465-489
Author(s): Marsha R. Eno, Michael D. Cameron

Application of Mass Spectrometry for Metabolite Identification

Journal: Current Drug Metabolism
Volume: 7 Issue: 5 Year: 2006 Page: 503-523
Author(s): Shuguang Ma, Swapan K. Chowdhury, Kevin B. Alton

Is it Possible to More Accurately Predict which Drug Candidates will cause Idiosyncratic Drug Reactions

Journal: Current Drug Metabolism
Volume: 1 Issue: 2 Year: 2000 Page: 133-141
Author(s): J. P. Uetrecht

Analyses of Associations Between Reactive Oxygen Metabolites and Antioxidant Capacity and Related Factors Among Healthy Adolescents

Journal: Current Aging Science
Volume: 6 Issue: 3 Year: 2013 Page: 258-265
Author(s): Kazuyoshi Tamae,Toshiharu Eto,Kazuhiro Aoki,Shingo Nakamaru,Kazunori Koshikawa,Kazuhiko Sakuma,Takeshi Hirano

Reactive Metabolites in Early Drug Development: Predictive In vitro Tools

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 4 Year: 2015 Page: 538-550
Author(s): Olavi Pelkonen, Markku Pasanen, Ari Tolonen, Mikko Koskinen, Jukka Hakkola, Khaled Abass, Jaana Laine, Merja Hakkinen, Risto Juvonen, Seppo Auriola, Markus Storvik, Pasi Huuskonen, Timo Rousu, Maiju Rahikkala

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