Search Result "reactive metabolite generation"


Are Chemically Reactive Metabolites Responsible for Adverse Reactions to Drugs?

Journal: Current Drug Metabolism
Volume: 3 Issue: 4 Year: 2002 Page: 351-366
Author(s): D. P. Williams, N. R. Kitteringham, D. J. Naisbitt, M. Pirmohamed, D. A. Smith, B. K. Park

Review Article

Reactive Metabolites: Generation and Estimation with Electrochemistry Based Analytical Strategy as an Emerging Screening Tool

Journal: Current Analytical Chemistry
Volume: 16 Issue: 7 Year: 2020 Page: 811-825
Author(s): Maria Bandookwala,Kavya Sri Nemani,Bappaditya Chatterjee,Pinaki Sengupta

Extrahepatic Targets and Cellular Reactivity of Drug Metabolites

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 4 Year: 2015 Page: 408-437
Author(s): Hilmi Orhan

On Mechanisms of Reactive Metabolite Formation from Drugs

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 13 Issue: 5 Year: 2013 Page: 720-729
Author(s): Alf Claesson, Ola Spjuth

Review Article

Amino Acid and Biogenic Amine Adductions Derived from Reactive Metabolites

Journal: Current Drug Metabolism
Volume: 22 Issue: 14 Year: 2021 Page: 1076-1086
Author(s): Jiang Zheng,Ying Peng,Zhengyu Zhang

Formation/Fate of Reactive Metabolites from General Anesthetics and A Comparison of Toxic and Non-Toxic Analogues: A DFT Study

Journal: Drug Metabolism Letters
Volume: 6 Issue: 4 Year: 2012 Page: 221-234
Author(s): Sonam Bhatia, Vaibhav A. Dixit, Harish Jangra, Prasad V. Bharatam

Application of 1D and 2D 1H-NMR in the Structural Elucidation of a N-Glucuronidated Metabolite and Oxidized Metabolites Generated in Microsomal Incubation

Journal: Drug Metabolism Letters
Volume: 6 Issue: 4 Year: 2012 Page: 265-274
Author(s): Julius L. Apuy, April Bai, David Paisner, Sayee G. Hegde, Mehran F. Moghaddam

Conventional and Novel Approaches in Generating and Characterization of Reactive Intermediates from Drugs/Drug Candidates

Journal: Current Drug Metabolism
Volume: 12 Issue: 4 Year: 2011 Page: 383-394
Author(s): Hilmi Orhan, Nico P.E. Vermeulen

Gauging Reactive Metabolites in Drug-Induced Toxicity

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 4 Year: 2015 Page: 465-489
Author(s): Marsha R. Eno, Michael D. Cameron

Mechanism of Idiosyncratic Drug Reactions: Reactive Metabolites Formation, Protein Binding and the Regulation of the Immune System

Journal: Current Drug Metabolism
Volume: 3 Issue: 4 Year: 2002 Page: 367-377
Author(s): C. Ju, J. P. Uetrecht

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